Patients with cancer undergoing chemotherapy often have diarrhea, which may result from their treatment or Clostridium difficile infection (CDI). CDI diarrhea is an important diagnosis that can be missed if nurses are not vigilant in their assessments. Treatment for CDI diarrhea is different than that of chemotherapy- or radiation-induced diarrhea. If CDI diarrhea is not treated, it can become ...

Background Clostridium difficile infection (CDI) is a common cause of antibiotic-associated diarrhea and can be difficult to cure. Most patients with CDI present only colonopathy and in fewer cases extra intestinal features were described such as reactive arthritis (ReA). We present a series of cases with CDI-associated reactive arthritis (CDI-AReA), admitted between 2011-2014 in the National I...

Background. Diagnosis and management of Clostridium difficile infection (CDI) rely upon clinical assessments and diagnostic studies. Among diagnostic tests, lower gastrointestinal (GI) endoscopy in the setting of CDI remains controversial. Objective. To describe the role of lower endoscopy in CDI management. Methods. Retrospective study of lower endoscopies in CDI at four metropolitan hospitals...

Treatment of Clostridium difficile infection (CDI) has relied on 2 antimicrobial agents, metronidazole and vancomycin, since the recognition of this disease entity. While effective, these "inside the box" approaches to CDI management have the disadvantage of further microbial disruption of the host indigenous microflora. "Outside the box" therapies use non-antimicrobial approaches to management...

Despite advances in the diagnosis and treatment of Clostridium difficile infection (CDI) and prevention efforts to reduce the spread of C. difficile, CDI remains a significant challenge to healthcare systems worldwide. Further advances in prevention of CDI may need to focus on those who continue to be exposed to the organism and who are susceptible. Interventions directed toward this susceptibl...

Little research has evaluated the validity of the Coping Deficit Index (CDI) of the Rorschach Comprehensive System (CS). Because the CS Depression Index (DEPI) has frequently been found to yield false negatives, the CDI has been proposed as an alternative means of assessing social coping skills that may relate to depression. This study examined potential correlates of the CDI using the Personal...

Background. Clostridium difficile infections (CDI) are the main cause of healthcare associated diarrhea. Inappropriate use of antibiotics (AB) is a significant risk factor for CDI. The aim of this study is to determine the proportion of CDI patients who received inappropriate AB prior to developing CDI. Methods. This is a retrospective cohort study to assess the proportion of newly diagnosed CD...

BACKGROUND We conducted a systematic review of mathematical models of transmission dynamic of Clostridium difficile infection (CDI) in healthcare settings, to provide an overview of existing models and their assessment of different CDI control strategies. METHODS We searched MEDLINE, EMBASE and Web of Science up to February 3, 2016 for transmission-dynamic models of Clostridium difficile in h...

BACKGROUND Gut microbiota play a key role in maintaining homeostasis in the human gut. Alterations in the gut microbial ecosystem predispose to Clostridium difficile infection (CDI) and gut inflammatory disorders such as inflammatory bowel disease (IBD). Fecal microbiota transplantation (FMT) from a healthy donor can restore gut microbial diversity and pathogen colonization resistance; conseque...