نتایج جستجو برای: cd99
تعداد نتایج: 537 فیلتر نتایج به سال:
The aim of this study was the immunological characterization of glioblastoma cells. Glioblastoma cell lines were cultured in serum and serum-free neurobasal (NBE) medium conditions. These cell lines were characterized by flow cytometry, reverse transcription-polymerase chain reaction (RT-PCR), western blot and natural killer (NK) cell-cytotoxicity assays. A previously described NK cell expansio...
Primitive neuroectodermal tumor (PENETs) is an uncommon malignancy of bone and soft tissue witch rarely occurs in the kidney. In more than 90% of the cases, the tumor cells relieves a balanced translocation (11; 22) (q24; q12). Immunohistochemical staining may be required for diagnosis of PENET. The cells of tumor express CD99, vimentin, NSE, FL1 but do not express Ck, LCA, myogenin, and WT1. W...
Wilson MD, Cheung J, Martindale DW, Scherer SW, Koop BF. Comparative analysis of the paired immunoglobulin-like receptor (PILR) locus in six mammalian genomes: duplication, conversion, and the birth of new genes. Physiol Genomics 27: 201–218, 2006. First published August 22, 2006; doi:10.1152/physiolgenomics.00284.2005.—Many aspects of the immune system are controlled by homologous cell surface...
Purpose: Goal of this study was to identify mechanisms that limit efficacy of trabectedin (ET-743, Yondelis) in Ewing sarcoma (EWS), so as todevelop a clinical applicable combination therapy. Experimental Design: By chromatin immunoprecipitation, we analyzed EWS–FLI1 binding to the promoters of several target genes, such as TGFbR2, CD99, insulin-like growth factor receptor 1 (IGF1R), and IGF1, ...
Synovial sarcoma is a relatively common soft tissue malignancy that is characterized by a specific chromosomal t(X;18)(p11;q11) translocation. Transducin-like enhancer of split 1 (TLE1) has emerged as a useful marker for the diagnosis of synovial sarcoma. However, the diagnostic value of this antibody remains controversial. We investigated TLE1 expression in sixty-two fluorescence in situ hybri...
BACKGROUND Ewing Sarcoma (EWS) is a mesenchymal-derived tumor that generally arises in bone and soft tissue. Intensive research regarding the pathogenesis of EWS has been insufficient to pinpoint the early events of Ewing sarcomagenesis. However, the Mesenchymal Stem Cell (MSC) is currently accepted as the most probable cell of origin. MATERIALS AND METHODS In an initial study regarding a dee...
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