نتایج جستجو برای: cd26
تعداد نتایج: 686 فیلتر نتایج به سال:
CD26 is a T cell activation marker consisting in a type II transmembrane glycoprotein with dipeptidyl peptidase IV (DPPIV) activity in its extracellular domain. It has been described that DPPIV inhibition delays the onset of type 1 diabetes and reverses the disease in non-obese diabetic (NOD) mice. The aim of the present study was to assess the effect of MK626, a DPPIV inhibitor, in type 1 diab...
BACKGROUND Kidney transplantation (RTx) leads to amelioration of endothelial function in patients with advanced renal failure. Endothelial progenitor cells (EPCs) may play a key role in this repair process. The aim of this study was to determine the impact of RTx and immunosuppressive therapy on the number of circulating EPCs. METHODS We analyzed 52 RTx patients (58±13 years; 33 males, mean ±...
In their interesting study on the concomitant reduction in inflammatory and oxidative stress and mean amplitude of glycemic excursions (MAGE) following treatment with dipeptidyl peptidase-IV (DPP-4) inhibitors, sitagliptin and vildagliptin, in patients with type 2 diabetes, Rizzo et al. (1) propose that the reduction in MAGE leads to the reduction in indices of oxidative and inflammatory stress...
Differential display of the integrins CD103 and CD11b are widely used to distinguish two major dendritic cell (DC) subsets in nonlymphoid tissues. CD103(+) DCs arise from FLT3-dependent DC precursors (preDCs), whereas CD11b(hi) DCs can arise either from preDCs or FLT3-independent monocytes. Functional characterization of these two lineages of CD11b(hi) DCs has been hindered by the lack of a wid...
CD26 is a 110-kDa multifunctional molecule having dipeptidyl peptidase IV (DPPIV) enzyme activity and is present on the surface of human T cells. Soluble CD26 (sCD26) exists in human blood and enhances the proliferation of peripheral T lymphocytes induced by tetanus toxoid (TT). The mechanisms by which CD26 enhances the activation of T cells and monocytes remain to be fully elucidated. In this ...
چکیده مقدمه: شایع‌ترین شکل لیشمانیا نوع پوستی آن یعنی سالک است که ضایعه‌ای جلدی بوده و معمولا با به جای گذاشتن جوشگاه ناخوش آیندی خودبخود بهبود می‌یابد اگر چه بندرت ممکن است بیماری به شکل غیر بهبود یابنده ظهور کند که به درمان‌های رایج نیز مقاوم خواهدبود پاسخTh1 در شکل بهبود یابنده و پاسخ Th2 در شکل غیربهبودیابنده بیماری نشان داده شده است. از طرف دیگر نشانگرهای CD26 و CD30 مولکولهائی سطحی هس...
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