The effects of dietary antioxidant supplementation on oxidative stress and life span are confused. We maintained C57BL/6 mice at 7 +/- 2 degrees C and supplemented their diet with alpha-tocopherol from 4 months of age. Supplementation significantly increased (p = 0.042) median life span by 15% (785 days, n = 44) relative to unsupplemented controls (682 days, n = 43) and also increased maximum l...

The purpose of this study was to test the hypothesis that creatine (Cr) supplementation may promote an additional hypertrophic effect on skeletal muscle independent of a higher workload on Cr-supplemented trained muscle compared with Cr-nonsupplemented trained muscle. Male Wistar rats (2-3 months old, 250-300 g) were divided randomly into 4 groups (n = 8 per group): nontrained without Cr supple...

Ingestion of an acute dose of phosphate has been shown to attenuate energy intake in the subsequent meal. This raises the question of whether the practice of phosphate supplementation over a number of days by athletes to enhance performance also influences energy intake. This study investigated the effect of 6 d of phosphate supplementation on appetite and energy intake, as well as aerobic capa...

Many studies have reported that selenium (Se) has a close relationship with autoimmune thyroiditis (AIT). The therapeutic effect of Se supplementation in AIT treatment remains unclear. The objective of the present study was to determine the efficacy of Se supplementation for the treatment of AIT. A structured literature search was undertaken to identify all randomized controlled trials conducte...

OBJECTIVE To systematically review randomized controlled trials comparing the effect of supplementation with multiple micronutrients versus iron and folic acid on pregnancy outcomes in developing countries. METHODS MEDLINE and EMBASE were searched. Outcomes of interest were birth weight, low birth weight, small size for gestational age, perinatal mortality and neonatal mortality. Pooled relat...

An oxidative burst occurs during pregnancy due to the large consumption of oxygen in the tissues and an increase in metabolic demands in response to maternal physiological changes and fetal growth. This study aimed to determine the oxidative profile and activity of δ-aminolevulinate dehydratase (δ-ALA-D) in pregnant women who received iron supplementation. Oxidative stress parameters were evalu...

This experiment studied the effects of whole yeast cell product supplementation on broiler production parameters, fecal coccidial oocyst counts, and local and systemic immune parameters following an experimental coccidial infection. Birds were fed 0, 0.1, or 0.2% whole yeast cell product (CitriStim). At 21 d of age, birds were challenged with live coccidial oocysts. Supplementation with whole y...

OBJECTIVE To examine the nature of media coverage of vitamin D in relation to its role in health and the need for supplements. DESIGN Media content analysis. SETTING Print articles from elite newspapers in the UK, the USA and Canada. PARTICIPANTS 294 print newspaper articles appearing over 5 years (2009-2014). RESULTS Newspaper coverage of vitamin D generally supported supplementation. ...

Iron deficiency is the most common and widespread nutritional disorder in the world, affecting millions of people in both nonindustrialized and industrialized countries. We estimated the costs, effects, and cost-effectiveness of iron supplementation and iron fortification interventions in 4 regions of the world. The effects on population health were arrived at by using a population model design...

the effect of yeast culture (saccharomyces cerevisiae) supplementation on laying hen diets was tested against flavomycin supplementation during 12 weeks, using 112 brown bovans laying hens, 52 week-old, divided into 7 equal groups fed on a basal diet containing 18.8% crude protein and 2810 kcal/kg me (metabolizable energy) feed. three groups were supplemented with 3 different levels of commerci...