Objective. To examine the utility of the Framingham risk score (FRS) in estimating cardiovascular risk in psoriasis. Methods. We compared the predicted 10-year risk of cardiovascular events, namely, cardiovascular death, myocardial infarction, heart failure, percutaneous transluminal coronary angioplasty, and coronary artery bypass grafting using the FRS, to the observed risk of cardiovascular ...

1287 cular risks of rosiglitazone led to a major change in FDA policy regarding the approval of all new diabetes drugs. From a cardiovascular perspective, rosiglitazone, saxagliptin, and alogliptin appear to be relatively safe. It is disappointing, however, that neither intensive glycemic control nor the use of specific diabetes medications is associated with any suggestion of cardiovascular be...

BACKGROUND AND PURPOSE The prevalence of atrial fibrillation increases with age, but age-specific data on the incidence of stroke and death in anticoagulated patients with atrial fibrillation are more limited, particularly with regard to comparisons of relative risks of clinical outcomes between the different age strata in relation to quality of anticoagulation control among warfarin users. M...

BACKGROUND Receiving a cancer diagnosis is a stressful event that may increase risks of suicide and cardiovascular death, especially soon after diagnosis. METHODS We conducted a cohort study of 342,497 patients diagnosed with prostate cancer from January 1, 1979, through December 31, 2004, in the Surveillance, Epidemiology, and End Results Program. Follow-up started from the date of prostate ...

BACKGROUND Multivitamin supplementation in pregnant women may reduce the risks of cardiovascular defects, oral clefts, and urinary tract defects in their infants. We evaluated whether the folic acid component of multivitamins is responsible for the reduction in risk by examining the associations between maternal use of folic acid antagonists and these congenital malformations. METHODS We comp...

ramadan is considered as holy month of muslims worldwide. during this month, most able-bodied muslim adults refrain from foods, drinks, smoking, and medications from dawn until sunset. in islamic rules, patients and those for whom fasting may have major health risks are exempted from fasting during ramadan. there is still no consensus regarding the effects of ramadan fasting, as a unique opport...

ramadan fasting during the month of ramadan is a religious obligation, practiced by millions of people around the world. ramadan fasting is essentially a fundamental change in lifestyle for one lunar month. this type of fasting may have significant effects on lipid profile. although there is no scientific consensus about the effects of fasting on cardiovascular risks such as changes in lipid pr...

an increase in c-reactive protein inflammatory indicator and lipid profile is accompanied with an increase in cardiovascular risks. however, the effect of resistance exercises on these cardiovascular risk factors in females is unknown.the aim of this study was to examine the effect of 12 weeks of circuit exercise on c-reactive protein and lipid profile in inactive women.for this purpose, 24 you...

The Federal Institute for Risk Assessment (BfR) below assesses a study from the Netherlands which provides valuable information on the unwanted effects of plant sterols on human retinal microvessels. Retinal vessels analysis is increasingly used for early diagnosis of cardiovascular risks. The findings of the study indicate that intake of plant sterols may entail cardiovascular risks for health...

BACKGROUND Although running is a popular leisure-time physical activity, little is known about the long-term effects of running on mortality. The dose-response relations between running, as well as the change in running behaviors over time, and mortality remain uncertain. OBJECTIVES We examined the associations of running with all-cause and cardiovascular mortality risks in 55,137 adults, 18 ...