Narcolepsy type 1 (NT1) is a lifelong disorder of sleep-wake dysregulation defined by clinical symptoms, neurophysiological findings, and low hypocretin levels. Besides role in sleep, hypocretins are also involved regulation heart rate blood pressure. This literature review examines data on the autonomic effects deficiency evidence about how narcolepsy associated with multiple cardiovascular ri...

Obstructive sleep apnea (OSA) has been strongly associated with several cardiovascular disorders during the past decade, and studies suggested that there might be a causal relationship. Recent studies have described several pathophysiologic mechanisms that are active in OSA and may participate in the development of cardiovascular disorders. Primarily, the repetitive respiratory events that occu...

Phenytoin (Diphenyl Hydantoin or Dilantin) is highly effective and widely prescribed anticonvulsant agent used in the treatment of grand mal and psychomotor epilepsy. Phenytoin has been used to treat thought, mood and Behavior disorders, cardiovascular disorders, Neuro muscular disorders, gastrointestinal disorders, Endocrine disorders.

Whereas the association of depression with cardiovascular disease is well established, the literature relating to anxiety disorders and cardiovascular disease is much less developed. There have been several studies which have examined the association of anxiety disorders with cardiovascular diagnoses, in particular with hypertension, an independent risk factor both for myocardial infarction and...

BACKGROUND We herein evaluate the Spanish population's trends in health burden by comparing results of two Global Burden of Diseases, Injuries, and Risk Factors Studies (the GBD studies) performed 20 years apart. METHODS Data is part of the GBD study for 1990 and 2010. We present results for mortality, years of life lost (YLLs), years lived with disability, and disability-adjusted life years ...