OBJECTIVE The aim of this article is to illustrate, by means of case reports on occupational exposure in four men with cancer, the hazards of previous and ongoing carcinogenic exposures in ships' engine rooms. Several cases of cancer occurred within a few years among the engine room crew of a passenger ferry. An investigation was undertaken to establish the number of cases, the types of cancers...

AIMS To investigate the relation between exposure to pesticides, polycyclic aromatic hydrocarbons (PAHs), diesel exhaust, metal dust, metal fumes, and mineral oil in relation to prostate cancer incidence in a large prospective study. METHODS This cohort study was conducted among 58,279 men in the Netherlands. In September 1986, cohort members (55-69 years) completed a self-administered questi...

Polycyclic aromatic hydrocarbons (PAHs) are a group of organic pollutants widely distributed in the atmosphere and well known for their carcinogenic mutagenic properties. Over last two decades, research about atmospheric PAHs has been focused urban industrial areas, while less attention given to rural areas. This study aims contribute filling this gap by analyzing levels, sources associated hea...

Cancer is a multistage multimechanism process involving gene and/or chromosomal mutations (genotoxic events), altered gene expression at the transcriptional, translational, and post-translational levels (epigenetic events), and altered cell survival (proliferation and apoptosis or necrosis), resulting in an imbalance of the organism's homeostasis. Maintenance of the organism's homeostasis depen...

Due to increasing energy demand and limited fossil fuels, renewable energy sources have gained in importance. Particulate matter (PM) in general, but also PM from the combustion of wood is known to exert adverse health effects in human. These are often related to specific toxic compounds adsorbed to the PM surface, such as polycyclic aromatic hydrocarbons (PAH), of which some are known human ca...

Several industrial activities around the Niger Delta region have contributed to widespread contamination of marine ecosystems with organochlorine compounds (OCs), petroleum products that are a source polycyclic aromatic hydrocarbons (PAHs). These pollutants tend be persistent in environment and also often highly toxic biota. The study was therefore, aimed at determining concentrations organic (...

Subsurface contaminants such as coal tar, creosote, diesel fuel, and other petroleum-derived materials typically exist as very complex chemical mixtures. Risk assessment is useful for site management if a single metric can represent the composition-dependent risk profile of the mixture. This paper examines the factors governing human health risk assessment for multicomponent nonaqueous phase li...

Corresponding Author: Arif, A., () Gene Expression Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi-110025 Email: [email protected] P a te l e t a l. 2 0 1 4 J o u rn a l o f In n o v a ti v e B io lo g y hrysene is a colorless to white, crystalline solid. It is also known as benzo(a)phenanthrene. It is most often found as the gaseous by-product from the incomplete co...

Polycyclic aromatic hydrocarbons (PAHs) are widely distributed in soil and difficult to degrade, posing a great threat the ecological environment human health. Therefore, research on distribution characteristics risks of PAHs is significance protect ecosystem Taking typical chemical industry park Chongqing as an example, spatial content 54 topsoil samples area were analyzed, pollution was evalu...

Polycyclic aromatic hydrocarbons (PAHs) cover a wide range of structurally related compounds which differ greatly in their carcinogenic potency. PAH exposure usually occurs through mixtures rather than individual compounds. Therefore, we assessed whether the effects of binary PAH mixtures on gene expression, DNA adduct formation, apoptosis and cell cycle are additive compared with the effects o...