BACKGROUND The diffusing capacity of the lungs for carbon monoxide (D(LCO)) is commonly measured during pulmonary function testing (PFT). Although adjustment of the measured D(LCO) for an elevated baseline carboxyhemoglobin level is recommended, carboxyhemoglobin is not routinely measured, which may reduce the accuracy of D(LCO) measurements. We sought to assess the utility of routine carboxyhe...

Çalışma ortamlarında çalışanların sağlık ve güvenliğini olumsuz etkileyen tehlike kaynaklarının başında kimyasal tehlikeler gelmektedir. Basit boğucu, irritan boğucu olarak sınıflandırılan gaz formundaki kimyasallar ise çalışma ortamları için ciddi riskler taşımaktadır.
 Bu çalışmada egzoz gazlarına maruz kalan Gümüşhane ilindeki benzin dağıtıcıları, taksi-otobüs şoförleri otomotiv sanayi ...

Aim: The primary aim of this study is to evaluate patients who present the emergency department with atypical symptoms in terms occult Carbon monoxide (CO) poisoning, and secondary compare invasive non-invasive values Carboxyhemglobin (COHb) levels high CO levels.
 Material Method: This prospective descriptive was conducted on 2775 adult visited Emergency Department (ED) between January 1 ...

In a cross-sectional study carboxyhaemoglobin (COHb) levels in tobacco smokers were found to provide a better indication of a person's risk of having developed certain atherosclerotic diseases, including ischaemic heart disease, than the smoking history. In the age group 30-69 years a person with a COHb level of 5% or more was found to be 21 times (lower 95% confidence limit 3.3 times) as likel...

An artificial hybrid hemoglobin cu(Co)P(Fe), the (Y and p subunits of which contain cobaltous protoporphyrin IX and ferrous protoporphyrin IX, respectively, and its complementary hybrid cu(Fe)P(Co), were prepared and examined by electron paramagnetic resonance spectroscopy. The fully oxy EPR spectra of cu(Co)p(Fe) and cu(Fe)P(Co) differ in their hyperfine splitting from each other, showing diff...

The effect of a single administration of aromatic hydrocarbons (AHCs) on the metabolic activity responsible for the biotransformation of dichloromethane (DCM) to carbon monoxide (CO) was investigated using adult female rats. In rats treated orally with benzene (1.5 ml kg-1), toluene (2.0 ml kg-1) or m-xylene (2.0 ml kg-1) 16-24 h prior to DCM (3 mmol kg-1, i.p.), the carboxyhaemoglobin (COHb) l...

A quick and accurate method of determining the concentration of carboxyhaemoglobin (COHb) in blood has been developed. The method uses a dual wavelength double beam spectrophotometer in the 1st derivative mode, linked to a digital voltmeter (DVM), with the two beams set 3 nm apart around an isobestic point of reduced haemoglobin (Hbred) and carboxyhaemoglobin at 579 nm. The 1st derivative mode ...

The physiological gaseous molecule, carbon monoxide (CO) becomes a subject of extensive investigation due to its vasoactive activity throughout the body but its role in gastroprotection has been little investigated. We determined the mechanism of CO released from its donor tricarbonyldichlororuthenium (II) dimer (CORM-2) in protection of gastric mucosa against 75% ethanol-induced injury. Rats w...

CAN J ANESTH 55: 2 www.cja-jca.org February, 2008 A 60-yr-old lady with HbM Saskatoon and congenital methemoglobinemia was scheduled for mastectomy. Clinical examination confirmed cyanosis but she had no symptoms due to methemoglobinemia and no history suggestive of cardiac or respiratory problems. Her electrocardiogram was normal and arterial blood gas (ABG) values on room air were: pH = 7.52,...

Background: carbon monoxide (CO) may play a role in pathophysiology of airway diseases. School children are at risk of exposure to environmental smoke. Adequate data regarding are not available. The measurement of exhaled CO level may provide an immediate, non-invasive method of fractional concentrations of CO in expired air. Exhaled CO levels & Carboxyhaemoglobin (COHb) reflects the exposure t...