BACKGROUND The insecticide resistance status of the malaria vector Anopheles funestus and the underlying resistance mechanisms remain uncharacterised in many parts of Africa, notably in Benin, West Africa. To fill this gap in our knowledge, we assessed the susceptibility status of a population of this species in Pahou, Southern Benin and investigated the potential resistance mechanisms. METHO...

In the title compound, 1.70C(14)H(14)N(+)·0.15C(28)H(28)N(2) (2+)·2C(6)H(5)O(3)S(-), the monocation exists in the E configuration with respect to the ethenyl C=C double bond and is close to planar, the dihedral angle between the pyridinium and phenyl ring being 5.20 (13)°. The dication lies about an inversion centre. In the crystal, the dication occupies almost the same site occupied by monocat...

A crystal structure of a carbamate of 2-amino-2-methyl-1-propanol (AMP-carbamate) has been elucidated and its structural and electronic properties investigated by density functional theory calculations and natural bond orbital analyses.

In the title mol-ecule, C(28)H(33)FN(2)O(5)S, the mean plane about the tertiary amine group (sum of the angles subtended at the sp(2)-hybridized N atom = 359.7°) forms a dihedral angle of 16.66 (6)° with the phenyl ring adjacent to the carbamate group. The sulfonamide benzene ring and the hy-droxy group lie to either side of the C(2)NS plane, whereas the benzyl-phenyl (connected to the N atom) ...

Acrylamide structurally resembles vinyl carbamate, a proposed proximate carcinogenic form of ethyl carbamate. To test the hypothesis that acrylamide should possess carcinogenic properties, it was tested in the Salmonella-microsome assay for point mutation, as a skin tumor initiator in the Sencar mouse, and for its ability to induce lung adenomas in the A/J mouse. Acrylamide was found to be with...

The crystal structures of three methyl-ated hydrazine carbamate derivatives prepared by multi-step syntheses from l-serine are presented, namely benzyl N-{(E)-1-[2-(4-cyanobenzylidene)-1-methylhydrazinyl]-3-hydroxy-1-oxopro-pan-2-yl}carbamate, C20H20N4O4, tert-butyl N-{(E)-1-[2-(4-cyanobenzylidene)-1-methylhydrazinyl]-3-hydroxy-1-oxopropan-2-yl}carbamate, C17H22N4O4, and tert-butyl N-[(E)-1-(2-...

Enzymatic synthesis of carbamoyl phosphate Carbamoyl phosphate is synthesized irreversibly by carbamoyl-phosphate synthase (CPS; EC6.3.4.16 and EC 6.3.5.5) in the first step of the routes of biosynthesis of pyrimidines, arginine and urea. In most bacteria, including Escherichia cofi, the same CPS is used for arginine and pyrimidine synthesis, whereas in higher organisms different CPS enzymes ar...

background: carbaryl is a carbamate insecticide widely used to control pests in agriculture and farm. carbaryl adversely affect the reproductive endocrine systems in animals. objective: the aim of this study was to evaluate carbaryl effects on the pituitary-gonad axis in rats. materials and methods: in this experimental - analytical study, 60 adult male rats were divided into four equal groups:...