نتایج جستجو برای: caprolactone scaffold

تعداد نتایج: 26001  

Journal: :Acta biomaterialia 2011
Jorge M Sobral Sofia G Caridade Rui A Sousa João F Mano Rui L Reis

Scaffolds produced by rapid prototyping (RP) techniques have proved their value for tissue engineering applications, due to their ability to produce predetermined forms and structures featuring fully interconnected pore architectures. Nevertheless, low cell seeding efficiency and non-uniform distribution of cells remain major limitations when using such types of scaffold. This can be mainly att...

2011
Mukesh K. Gupta Joel M. Walthall Raghav Venkataraman Spencer W. Crowder Dae Kwang Jung Shann S. Yu Tromondae K. Feaster Xintong Wang Todd D. Giorgio Charles C. Hong Franz J. Baudenbacher Antonis K. Hatzopoulos Hak-Joon Sung

Myocardial infarction results in extensive cardiomyocyte death which can lead to fatal arrhythmias or congestive heart failure. Delivery of stem cells to repopulate damaged cardiac tissue may be an attractive and innovative solution for repairing the damaged heart. Instructive polymer scaffolds with a wide range of properties have been used extensively to direct the differentiation of stem cell...

Tissue-engineering scaffolds provide biological and mechanical frameworks for cell adhesion, growth, and differentiation. Nanofibrous scaffolds mimic the native extracellular matrix (ECM) and play a significant role in formation and remodeling of tissues and/or organs . One way to mimic the desired properties of fibrous ECM is adding nanoparticles into the polymer matrix. In the current study, ...

2005
S. Khalil

Purpose – To introduce recent research and development of biopolymer deposition for freeform fabrication of three-dimensional tissue scaffolds that is capable of depositing bioactive ingredients. Design/methodology/approach – A multi-nozzle biopolymer deposition system is developed, which is capable of extruding biopolymer solutions and living cells for freeform construction of 3D tissue scaffo...

Journal: :Materials science & engineering. C, Materials for biological applications 2016
Soumyaranjan Mohanty Kuldeep Sanger Arto Heiskanen Jon Trifol Peter Szabo Marin Dufva Jenny Emnéus Anders Wolff

Limitations in controlling scaffold architecture using traditional fabrication techniques are a problem when constructing engineered tissues/organs. Recently, integration of two pore architectures to generate dual-pore scaffolds with tailored physical properties has attracted wide attention in tissue engineering community. Such scaffolds features primary structured pores which can efficiently e...

Journal: :Journal of the Royal Society, Interface 2012
Vincenzo Guarino Francesco Urciuolo Marco A Alvarez-Perez Benedetto Mele Paolo A Netti Luigi Ambrosio

The development of composite scaffolds with well-organized architecture and multi-scale properties (i.e. porosity, degradation) represents a valid approach for achieving a tissue-engineered construct capable of reproducing the medium- and long-term in vitro behaviour of hierarchically complex tissues such as spongy bone. To date, the implementation of scaffold design strategies able to summariz...

Journal: :International Journal of Molecular Sciences 2021

The aim was to examine the efficiency of a scaffold made poly (L-lactic acid)-co-poly(?-caprolactone), collagen (COL), polyaniline (PANI), and enriched with adipose-derived stem cells (ASCs) as nerve conduit in rat model. P(LLA-CL)-COL-PANI optimized electrospun into tubular-shaped structure. Adipose tissue from 10 Lewis rats harvested for ASCs culture. A total 28 inbred male underwent sciatic ...

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