The usage of reovirus has reached phase II and III clinical trials in human cancers. However, this is the first study to report the oncolytic effects of reovirus in veterinary oncology, focusing on canine mast cell tumor (MCT), the most common cutaneous tumor in dogs. As human and canine cancers share many similarities, we hypothesized that the oncolytic effects of reovirus can be exploited in ...

We aimed to establish a reliable method of localizing an impacted maxillary canine on the sole basis of assessment of a single panoramic radiograph, and to determine the validity and reproducibility of the method. Panoramic radiographs of 50 subjects with a total of 68 impacted canines were analysed. The Canine Incisor Index (CII), Canine Canine Index (CCI), control Canine Incisor Index (c-CII)...

The objectives of this study were to develop a serum-free system for culturing canine oral keratinocytes, the construction and characterization of a canine ex vivo produced oral mucosa equivalent (EVPOME), and transduction green fluorescent protein (GFP) into keratinocytes as a post-grafting tracking marker. Dissociated canine buccal mucosa keratinocytes were cultured in a chemically defined se...

Cancer-associated stroma (CAS) plays a key role in cancer initiation and progression. Spontaneously occurring canine mammary carcinomas are viewed as excellent models of human breast carcinomas. Considering the importance of CAS for human cancer, it likely plays a central role in canine tumours as well. So far, however, canine CAS lacks characterisation, and it remains unclear whether the biolo...

Abstract The purpose of this study was to explore benefits interacting with a canine on anxiety, stress, depression, and wellbeing in Higher Education ( HE ) students. Sixty participants took part randomized controlled trial. Assigned either the canine-assisted intervention CAI or control group, group interacted whereas watched an unrelated slideshow. Anxiety, measures were completed pre- post-...

BACKGROUND Dogs are associated with more than 60 zoonotic diseases among which, parasitosis and, in particular, helminthosis, can pose serious public-health concerns worldwide. Many canine gastrointestinal parasites eliminate their dispersion elements (eggs, larvae, oocysts) by the faecal route. The quantity of canine faeces deposited on public and private property in cities worldwide is both a...

Background: The assisted reproductive techniques (ARTs) such as in vitro fertilization, embryo transfer and cryopreservation of gametes have considerably contributed to the development of biomedical sciences in addition to improved breeding in domestic animals and infertility treatment in humans. However, ARTs used in canine species have strictly limited utility when compared with other mammali...

Canine hepatozoonosis is a tick-borne protozoan disease spread by hard ticks of the Ixodidae family. Although this illness has been seen in numerous locations Türkiye, its existence Batman and Van provinces yet to be confirmed. The purpose research was look into canine stray dogs from two distinct areas Türkiye using conventional polymerase chain reaction (PCR). Between 2019 2021, blood samples...

Impaction and eruption disturbance of permanent teeth are frequently encountered in orthodontic practice. The canine play an important role both functionally esthetically. Eruption a maxillary canine, if left untreated, can cause not only disturbed jaw movement esthetic problems, but also root resorption adjacent teeth, thus should be diagnosed treated appropriately. In this report, we present ...