The use of antiovulatory contraceptive pills has increased rapidly in recent years and the World Health Organisation estimates that they are being taken by more than 20 million women throughout the world. In Britain, the Committee on the Safety of Drugs has stated that contraceptive pills are employed by over a million and a half women at the present time. The increasing use of these preparatio...

AIMS To compare the serum concentrations of itraconazole and hydroxyitraconazole after treatment with itraconazole cyclodextrin solution and itraconazole capsules in human immunodeficiency virus (HIV) positive patients with oral candidosis. METHODS The pharmacokinetics of itraconazole and its active metabolite hydroxy-itraconazole were assessed on days 1 and 7 of therapy in acquired immunodef...

OBJECTIVE To monitor yeasts isolated from women during and between episodes of recurrent vulvo-vaginal candidosis (VVC) to determine whether vaginal relapse or re-infection occurred. METHODS Women presenting at the genitourinary medicine clinic with signs and symptoms of VVC were recruited to the study (n = 121). A vaginal washing, high vaginal swab (HVS) and rectal swab were taken and the wo...