نتایج جستجو برای: cancer drug

تعداد نتایج: 1431186  

Mestastatic prostate cancer cells (MPCCs) frequently metastasize to bone, which is a “favorite soil” for colonization and proliferation of MPCCs. Prostate cancer bone mestastasis is tightly associated with tumor-induced bone lesions, most commonly caused from the etiological imbalance between osteoblastic bone formation and osteoclastic bone resorption, and from the anti-tumor immune response. ...

Breast cancer is the most common cancer in women worldwide. Current cancer treatments have multiple side effects, including damage to healthy cells, drug resistance and disease recurrence. Therefore, new therapeutic strategies are needed to achieve fewer toxicity and side effects. Several studies suggest that phytochemicals could be considered as appropriate choices for cancer prevention and...

Background and purpose: Nowadays, multi-drug regimens or combination therapy are new approaches in cancer treatment that combine two or several therapeutic agents. Combination therapy aims at improving the therapeutic efficacy of anticancer drugs while reducing toxicity and preventing drug resistance. The aim of this study was to determine the synergistic effect of combined clarithromycin and d...

Journal: :nanomedicine journal 0
nosrat madadi mahani chemistry department, payame noor university, tehran, iranسازمان اصلی تایید شده: دانشگاه پیام نور تهران (payame noor university)

objective(s): the novel 7-hydroxycoumarinyl gallates derivatives are detected in many pharmaceutical compounds like anticancer and antimicrobial agents. whereas carbon nanotubes (cnts) have been discussed for nanomedicine applications and in particular as drug delivery systems. the capability of armchair (5, 5) swcnt -based drug delivery system in the therapy of anticancer has been investigated...

Journal: :international journal of hematology-oncology and stem cell research 0
hamidreza fasehee stem cell and regenerative medicine group, national institute of genetic engineering and biotechnology (nigeb), tehran , iran ardeshir ghavamzadeh hematology, oncology and stem cell transplantation research center, shariati hospital, tehran university of medical science, tehran, iran kamran alimoghaddam hematology, oncology and stem cell transplantation research center, shariati hospital, tehran university of medical science, tehran, iran seyed h. ghaffari hematology, oncology and stem cell transplantation research center, shariati hospital, tehran university of medical science, tehran, iran shahab faghihi stem cell and regenerative medicine group, national institute of genetic engineering and biotechnology (nigeb), tehran , iran

background: disulfiram is oral aldehyde dehydrogenase (aldh) inhibitor that has been used in the treatment of alcoholism. recent studies show that this drug has anticancer properties; however, its rapid degradation has limited its clinical application. encapsulation of disulfiram polymeric nanoparticles (nps) may improve its anticancer activities and protect rapid degradation of the drug. mater...

Journal: :Oncology reports 2014
Jianchao Li Yonghong Zhang Yutao Gao Yuqian Cui Hua Liu Mi Li Yongjie Tian

The expression of HNF1 homeobox B (HNF1B) is associated with cancer risk in several tumors, including ovarian cancer, and its decreased expression play roles in cancer development. However, the study of HNF1B and cancer is limited, and its association with drug resistance in cancer has never been reported. On the basis of array data retrieved from Oncomine and Gene Expression Omnibus (GEO) onli...

Journal: :iranian journal of medical sciences 0
zahra eslami nejad elham ghafouri zahra farahmandi-nia behjat kalantari fereshteh saffari

background: blood stream infection is one of the main causes of morbidity and mortality in patients with cancer. the purpose of this study was to evaluate the prevalence of aerobic and anaerobic-bacteremia in hospital inpatients with cancer and to determine the antibiotic resistance profile in isolated organisms in kerman, southeast iran.   methods: total of 240 blood cultures from 136 patients...

ژورنال: کنترل 2021

Recently, Carbon Nano (CN) structures are widely used in medical applications, especially the detection and treatment of cancer disease. Among various types of CNs, Carbone Nano Tubes (CNTs) attracted many researchers' attention to consider them toward clinical application. Regarding the intrinsic structure of CNTs, they can be used widely in drug delivery applications. Functionalized CNTs and ...

Journal: :Frontiers in control engineering 2022

Recent advancements in cybergenetics have led to the development of new computational and experimental platforms that enable us robustly steer cellular dynamics by applying external feedback control. Such technologies never been applied regulate intracellular cancer cells. Here, we show silico adaptive model predictive control (MPC) can effectively be used simulated signalling Non-Small Cell Lu...

Journal: :Future Pharmacology 2022

Chloroquine (CQ) and hydroxychloroquine (HCQ) have been used to treat malaria autoimmune diseases for more than 70 years; they also immunomodulatory anticancer effects, which are linked autophagy autophagy-independent mechanisms. Herein, we review the pharmacokinetics, preclinical studies clinical trials investigating use of CQ HCQ as adjuvant agents in cancer therapy. We discuss their safety p...

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