Epilachna vigintioctopunctata is an important pest that causes considerable economic losses to many crops including egg-plants. The crude aqueous extracts of leaves from three indigenous plants namely Ricinus communis, Calotropis procera and Datura metel were used against this beetle aiming at its control under laboratory conditions. Larvicidal bioassays of the extracts showed the following ord...

The objective of the study is to explore the anticancer activity of di-(2-ethylhexyl) phthalate (DEHP) isolated from Calotropis gigantea flower against Ehrlich ascites carcinoma cells (EAC) in Swiss albino mice. The activity of DEHP was evaluated at doses of 10, 20 and 40 mg kg-1 body mass applied intraperitoneally. DEHP showed a significant decrease in viable cell count (p < 0.05), mass gain (...

Calotropis procera is a tropical medicinal plant known for its multiple curative effects on wide range of diseases. Current study has evaluated the antimitotic activity of the extracts of leaf and latex of C. procera on root meristem cells of Allium cepa. Onion bulbs were allowed to grow roots on moist cotton imbibed with solutions of test sample with known concentration of the extracts. Mitoti...

Calotropin isolated and characterized from the roots of Calotropis procera when administered to gerbils (25mg/kg b.wt) and rabbits (25mg; kg b.wt) each day for a period of 30 days inhibited the process of spermatogenesis. The population of spermatids was depleted by 65% and 94% in gerbils and rabbits. The seminiferous tubules and the Leydig cell nuclei diameters were reduced in both the species...

Ethanolic extract (50 %) of stems of Calotropis gigantea R. Br. (Asclepiadaceae) at doses of 250 and 500 mg kg-1 were studied for hepatoprotective activity in male Wistar rats with liver damage induced using carbon tetrachloride, 2 mL kg-1 twice a week. The protective effect of C. gigantea extract was compared with the standard drug silymarin. Various biochemical parameters such as aspartate am...

A phytochemical study on the flowe r of Calotropis gigantea (Linn.) using silica gel column chromatography and preparative thin layer chromatography, led to the first time isolation of Di-(2-ethylhexyl) phthalate (compound 1) and anhydrosophoradiol-3-acetate (compound 2). The structures of these compounds were confirmed by spectroscopic analyses (IR, HRTOFMS and NMR). The antibacterial and anti...

The protective effect of Calotropis gigantea flower extract in acute alcohol induced hepatotoxicity in rats was evaluated. A significant increase in the levels of enzyme markers of tissues damage (ALT, AST and ALP), lipid peroxidation (TBARS) and decreased serum vitamin C levels were observed in alcohol intoxicated rats as compared to control animals. Pretreatment with 250 and 500 mg/kg body we...

Calotropis proceran (Asclepidaceae) is an evergreen plant and widely distributed in Hormozgan province. This plant has the allelopathic properties including germination inhibition, plumule and radicle growth reduction. In this study the effect of different concentrations (0, 5, 10, 20, 40 and 60%) of dry leaf water extraction of this plant on the germination of cucumber (Cucumis sativus), tomat...