CONTEXT Intrauterine growth retard (IUGR) continues to be a significant perinatology problem at the end of this century. The nature of the etiologic agent, the time when the attack occurred during pregnancy and its duration affect the type of IUGR. OBJECTIVE To study the evolution of fetal pancreas and placenta between the 18th and 21st day of pregnancy in rats submitted to maternal protein-c...

It is well known that immunological functions are influenced by stressors . Psychological stressors influence also usual behaviors such as eating, sleep and exercise . In this paper, we report effects of emotional behavior, restriction, sleep deprivation or nutrition on immunological functions using animal model. Using mature cats which were implanted electrode in hypothalamus, emotional behavi...

To investigate the hypothesis that caloric restriction alters mitochondrial function in situ, intact hepatocytes were isolated from fully fed and calorie-restricted (55% of control food intake, 4 months duration) male Brown-Norway rats at 6 months of age, and various parameters were determined. Overall, the production of reactive oxygen species was not affected by caloric restriction, neither w...

Background: Calorie restriction without malnutrition is likely to improve cardiovascular risk factors. Objectives: The aim of this study was investigate calorie on markers cardiometabolic in overweight/obese adults with Methods: In a parallel controlled trial, patients overweight or obesity and one more factor were randomized modest reduced-calorie diet (75% the total calculated energy requirem...

Introduction: Fasting is a common ingredient of naturopathic prescription in India. However no studies have been conducted to establish the use, approach of naturopathy physicians towards fasting.The present study, a cross sectional survey was conducted to assess the attitude, use, belief and understanding about therapeutic fasting among the naturopathy physicians in India.Methods: A 12 item e-...

Calorie restriction (CR) is the most effective way to increase life span and delay the onset of age-related symptoms in animals. We have previously reported that CR affects a variety of physiological phenotypes in flies and results in dramatic behavioral, physical and demographic changes. Here we show effects of low and high calorie levels on the spontaneous physical activity of flies. Wild typ...

INTRODUCTION Neuroblastoma is a malignant pediatric cancer derived from neural crest cells. It is characterized by a generalized reduction of mitochondrial oxidative phosphorylation. The goal of the present study was to investigate the effects of calorie restriction and ketogenic diet on neuroblastoma tumor growth and monitor potential adaptive mechanisms of the cancer's oxidative phosphorylati...