An amphiphilic gelatin-iron oxide core/calcium phosphate shell (AGIO@CaP-DOX) nanoparticle was successfully synthesized as an efficient anti-cancer drug delivery system, where doxorubicin (DOX) as a model molecule was encapsulated by electrolytic co-deposition during CaP shell formation. The shell of CaP precipitate played a pivotal role, not only in acting as a drug depot, but also in renderin...

Pathological calcification is becoming recognized as an important feature in the dynamics of a variety of diseases, such as renal stone, atherosclerosis, pulp stones, scleroderma and arthritis, etc. from which millions of human beings suffer in all ages. Nanobacterium sanguineum is the first calcium phosphate mineral containing nanoorganism isolated from human blood that causes pathological dis...

the role of parathyroid hormone on stature in major beta-thalassemic patients   gr. moshtaghi kashanian phd 1 , a. ahmadi md2, mm. hayat bakhsh md3   1- assistant professor, dept. of biochemistry, faculty of medicine, university of medical sciences, kerman, iran   2- professor of pediaterics, university of medical sciences, kerman, iran   3- assistant professor of internal medicine, faculty of ...

Bone implants must be biocompatible and are usually built to promote osseointegration, e.g. by application of plasma spray calcium phosphate (CaP) coating. The risk of infection and biofilm formation on implant surfaces is a well-known problem. The combination of electrochemically deposited CaP coating with antibiotics may offer significant benefits. Here, we demonstrate an innovative in situ e...

abstract the objectives of this research was to evaluate the rhizospheric effects of wheat (triticum aestivum l.) on the status of various inorganic p fractions and total organic p in 10 calcareous soils amended with 1% (w/w) municipal sewage sludge from the refinery of shahrekord city under rhizobox conditions. thus, wheat plant was planted in completely randomized design with three replicatio...

In this study, linear alkyl-benzene calcium sulfonate nanoparticles were made using linear alkylbenzene. Calcium sulfonate nanoparticles are widely used as an additive in a variety of engine oils and have cleansing, anti-wear and anti-oxidant properties and anti-corrosion properties. In this method, a sulfonation set up was constructed and sulfonation reaction was carried out both directly and ...

It has long been known that oral or intravenous administration of phosphate salts lowers the serum calcium concentration in normal animals (1, 2) and in hypercalcemic human subjects (3-5). Recently , interest has been renewed in the clinical use of phosphate therapy to control life-threatening hypercalcemia because of the relative in-effectiveness or toxicity of other modes of therapy (6, 7). I...

statement of problem: dental caries is one of the most common chronic diseases in children. the balance between demineralization and remineralization of the decayed teeth depends on the calcium and phosphate content of the tooth surface. therefore, if a product such as casein phospho peptides - amorphous calcium phosphate (cpp- acp) which can significantly increase the availability of calcium a...

Titania and silica have been recognized as potential drug delivery system (DDS) carriers. For this application, controllable biocompatibility the suppression of initial burst are required, which can be provided by a calcium phosphate (CP) coating. However, it is difficult to control morphology CP coating on surface carrier particles owing homogeneous nucleation CP. In study, we report developme...

Amorphous calcium phosphate (aCaP) nanoparticles may trigger the osteogenic commitment of adipose-derived stem cells (ASCs) in vitro. The ASCs three human donors are investigated using basal culture medium DMEM to either 5 or 50 µg/mL aCaP suspension (control: no nanoparticles). After 7 14 days, cell marker genes, as well endothelial, osteogenic, chondrogenic, and adipogenic analyzed by qPCR. F...