Familial hypokalemic periodic paralysis is an autosomal-dominant channelopathy characterized by episodic muscle weakness with hypokalemia. The respiratory and cardiac muscles typically remain unaffected, but we report an atypical case of a family with hypokalemic periodic paralysis in which the affected members presented with frequent respiratory insufficiency during severe attacks. Molecular a...

the comparison of total and ionised serum calcium level in preeclamptic pregnant women and the women with normal pregnancy   z. salari md1*, n. eftekhari md2     1- assistan professor, dept of gynecology, university of medical sciences, kerman, iran 2- associated professor, dept of gynecology, university of medical sciences, kerman, iran     background: preeclampsia remains one of the important...

We studied and performed genetic linkage studies and mutational analysis on 1 1 patients from 5 unrelated kindreds with Andersen's syndrome (AS). Our data suggest AS is a distinct periodic paralysis occurring in the setting of either hyperor hypokalemia, with severe cardiac involvement (LQT) and distinct skeletal abnormalities whose gene defect is still unknown.

The Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease that is often associated with lung cancer which shares a common antigenic protein with the motor nerve terminal. The myasthenic weakness is caused by an antibody-induced reduction in the release of acetylcholine from the nerve terminal. This study was undertaken to determine the target of LEMS antibodies and specify the volta...