four hundred and eighty mixed-sex broiler chicks aged 3 hrs after hatching were allotted according to a completely random design in a 6 × 2 × 2 factorial schedule into 2 groups of 12 replications of 20 chicks each. the main experimental factors were fasting for 0, 6, 12, 24, 36, and 48 hrs after chick placement, calcium gluconate (ca-glu) injection (0 and 0.6 ml) and sex (male and female). inde...

2. Facultad de Medicina, Universidad Nacional Autónoma de México 7 Running title: Sr substitution of Ca prolongs inspiratory burst 8 9 Word count: 6816 10 Figures: 5 11 References: 67 12 Pages: 25 13 14 Correspondence should be addressed to: 15 Consuelo Morgado-Valle, Ph.D. 16 Centro de Investigaciones Cerebrales 17 Universidad Veracruzana 18 Berlin 7. Fracc. Montemagno Animas 19 C.P. 91190 Xal...

BACKGROUND Chronic kidney disease-mineral bone disorder (CKD-MBD), a newly defined disorder in patients with CKD, describes the interacting triad of (1) biochemical abnormalities of calcium, phosphorus and parathyroid hormone (PTH), (2) extraskeletal calcification and (3) abnormal bone. METHODS We studied the effects of the calcimimetic R-568, R-568 with calcium (R-568 + Ca) or calcium (Ca) a...

Glutamate release from rod photoreceptors is dependent on a sustained calcium influx through L-type calcium channels. Missense mutations in the CACNA1F gene in patients with incomplete X-linked congenital stationary night blindness implicate the Ca(v)1.4 calcium channel subtype. Here, we describe the functional and pharmacological properties of transiently expressed human Ca(v)1.4 calcium chann...

The contributions of electrogenic sodium/calcium exchange current ( I NaCa), calcium-activated chloride conductance [ I Cl(Ca)], and calcium-activated nonselective cation conductance to delayed afterdepolarizations (DAD) were examined. Nonselective cation channels were absent in canine M cells, since inhibition of I NaCa and I Cl(Ca)eliminated all calcium-activated currents without abolishing c...

Calcium sparks represent local, rapid, and transient calcium release events from a cluster of ryanodine receptors (RyRs) in the sarcoplasmic reticulum. In arterial smooth muscle cells (SMCs), calcium sparks activate calcium-dependent potassium channels causing decrease in the global intracellular [Ca2+] and oppose vasoconstriction. This is in contrast to cardiac and skeletal muscle, where spati...

Numerous hormones and neurotransmitters activate cells by increasing cytosolic calcium concentration ([Ca(2+)](i)), a key regulatory factor for many cellular processes. A pivotal feature of these Ca(2+) signals is the release of Ca(2+) from intracellular stores, which is followed by activation of extracellular calcium influx, allowing refilling of the stores by SERCA pumps associated with the e...

After incubation with 2-butylamino-2-demethoxy-hypocrellin A (2-BA-2-DMHA), photodynamically induced change in the cytoplasmic free calcium concentration ([Ca(2+)](i)) and its effect on cell damage were investigated in human gastric cancer (MGC-803). Fluorescence spectrophotometry measurement indicated that the photosensitization of MGC-803 by 2-BA-2-DMHA caused an increase in intracellular cal...

BACKGROUND Hypercalciuria is a frequent characteristic of hypertension. In this report we extend our earlier studies investigating the role of renal interstitial fluid calcium (ISF(Ca))(2+) as a link between urinary calcium excretion and blood pressure in the Dahl salt-sensitive (DS) hypertensive model. METHODS Dahl salt-sensitive and salt-resistant (DR) rats were placed on control (0.45%) an...