Epidemiological studies indicate a J-shaped relationship linking coffee consumption and cardiovascular risk, suggesting that moderate coffee consumption can be beneficial. Platelet aggregation is of critical importance in thrombotic events, and platelets play a major role in the aetiology of several CVD. The aim of this study was to evaluate the effect of coffee drinking on platelet aggregation...

Objective: To investigate the relationship between caffeine consumption among pregnant women in the UAE and spontaneous abortion and stillbirth. Methods: A retrospective cross-sectional survey has been conducted on 97 pregnant ladies randomly selected from Al Ain city in the UAE. Only pregnant women with caffeine intake were included in the study. Results: The results showed that: 61.9% of wome...

BACKGROUND Prior studies have found weak inverse associations between breast cancer and caffeine and coffee intake, possibly mediated through their effects on sex hormones. METHODS High-performance liquid chromatography/tandem mass spectrometry was used to quantify levels of 15 individual estrogens and estrogen metabolites (EM) among 587 premenopausal women in the Nurses' Health Study II with...

Beetroot juice, which is rich in nitrate (NO3 (-)), has been shown in some studies to decrease oxygen consumption (V̇o2) for a given exercise workload, i.e., increasing efficiency and exercise tolerance. Few studies have examined the effect of beetroot juice or nitrate supplementation on exercise metabolism. Eight healthy recreationally active males participated in three trials involving ingesti...

1378 CAFFEINE IS A WIDELY USED STIMULANT WITH MARKED VARIATIONS IN BEHAVIORAL RESPONSE BETWEEN INDIVIDUALS. POSITIVE BEHAVIORAL responses may include increased alertness and physical activity, although these may represent a withdrawal reversal mechanism operating in habitual caffeine users,1-3 whereas responses such as heightened nervousness and sleep disturbance would be considered negative.4-...

Caffeine is one of the most widely consumed psycho-stimulants in the world, yet little is known about its effects on brain oxygenation and metabolism. Using a double-blind, placebo-controlled, randomized cross-over study design, we combined transcranial Doppler ultrasound (TCD) and near-infrared spectroscopy (NIRS) to study caffeine's effect on middle cerebral artery peak blood flow velocity (V...