Coleus aromaticus (Benth, Family: Laminaceae), Indian Oregano native to India and Mediterranean, is well known for its medicinal properties. A preliminary study was undertaken to elucidate in vitro free radical scavenging potential and inhibition of lipid peroxidation by C.aromaticus hydroalcoholic extract (CAE). Anti-clastogenic and radioprotective potential of CAE were studied using micronucl...

The alternative sigma factor PvdS is required by Pseudomonas aeruginosa for initiation of transcription from pyoverdine (pvd) promoters. Two divergent PvdS-dependent promoters (pvdE and pvdF) were characterized by deletion analysis, and the minimal promoter region for each included a sequence element, the iron starvation (IS) box, that is present in other pvd promoters. Site-directed mutagenesi...

OBJECTIVES To determine both ventricular functions and tissue Doppler echocardiography (TDE)-derived myocardial performance index (MPI) in patients with coronary artery ectasia (CAE). SUBJECTS AND METHODS Twenty-five patients with CAE (13 men; mean age 57 ± 9 years) and 25 age- and sex-matched controls without CAE (8 men; mean age 54 ± 10 years) were enrolled in the study. Left and right vent...

Coronary artery ectasia (CAE) is a rare form of coronary artery disease. It has previously been shown that nitrate derivatives induce exertional angina in patients with CAE. Furthermore, there is limited data about the effects of other anti-ischemic agents in CAE. The aim of this study was to investigate the effect of trimetazidine on exercise performance in patients with CAE. The study populat...

Animals sample their environment through sensory neurons with often elaborately branched endings named dendritic arbors. In a genetic screen for genes involved in the development of the highly arborized somatosensory PVD neuron in C. elegans, we have identified mutations in kpc-1, which encodes the homolog of the proprotein convertase furin. We show that kpc-1/furin is necessary to promote the ...

Neurons receive excitatory or sensory inputs through their dendrites, which often branch extensively to form unique neuron-specific structures. How neurons regulate the formation of their particular arbor is only partially understood. In genetic screens using the multidendritic arbor of PVD somatosensory neurons in the nematode Caenorhabditis elegans, we identified a mutation in the ER stress s...

We present a novel convolutional auto-encoder (CAE) for unsupervised feature learning. A stack of CAEs forms a convolutional neural network (CNN). Each CAE is trained using conventional on-line gradient descent without additional regularization terms. A max-pooling layer is essential to learn biologically plausible features consistent with those found by previous approaches. Initializing a CNN ...

The objective of this study was to characterize the species composition and functional potential vaginal uterine microbiota at 1 wk postpartum in dairy cows diagnosed with or without purulent discharge (PVD) 3 postpartum. hypothesis that differences between (PVD+) (PVD−) PVD were dependent on parity breed. Cytobrush samples vagina uterus collected from 36 Holstein-Friesian (7 primiparous 29 mul...

The measurement of the thrombosis in myocardial infarction (TIMI) frame count is a simple method for evaluating coronary blood flow. Although it is well known that slow coronary flow is present in patients with coronary artery ectasia (CAE), the effects of coexisting stenosis and the severity of ectatic involvement on coronory flow have not been adequately studied. Thus, we examined (1) the eff...

The paper summarizes the current development of high-velocity oxygen–fuel coupled physical vapor deposition (HVOF-PVD) duplex coatings as protective candidates. Following a detailed historical overview HVOF and PVD technologies, fabrication methods for are presented. coating superimposes synergistic advantages deposited by PVD, where traditional weaknesses each technique modified to great certa...