I have carried out numerical first principles calculations of the pressure dependence of the elastic moduli for several ordered structures in the Aluminum-Lithium system, specifically FCC Al, FCC and BCC Li, L12 Al3Li, and an ordered FCC Al7Li supercell. The calculations were performed using the full potential linear augmented plane wave method (LAPW) to calculate the total energy as a function...

Metabolomics is a promising tool to gain new insights into early metabolic alterations preceding the development of hypertension in humans. We therefore aimed to identify metabolites associated with incident hypertension using measured data of serum metabolites of the European Prospective Investigation Into Cancer and Nutrition (EPIC)-Potsdam study. Targeted metabolic profiling was conducted on...

First principles calculations are preformed to systematically investigate the elastic and thermodynamic properties of Re2N at high pressure and high temperature. The Re2N exhibits a clear elastic anisotropy and the elastic constants C11 and C33 vary rapidly in comparison with the variations in C12, C13 and C44 at high pressure. In addition, bulk modulus B, elastic modulus E, and shear modulus G...

We consider an extension of the Markowitz mean}variance optimization framework to multiple return and risk scenarios. It is well known that asset return forecasts and risk estimates are inherently inaccurate. The method proposed provides a means for considering rival representations of the future. The optimal portfolio is computed, simultaneously with the worst case, to take account of all riva...

11 This paper proposes a new statistical technique for deciding which of two theories is better supported 12 by a given set of data while allowing for the possibility of drawing no conclusion at all. Procedurally 13 similar to the classical hypothesis test, the proposed technique features three, as opposed to two, 14 mutually exclusive data classifications: reject the null, reject the alternati...

Solid organ transplant recipients are at increased risk of epithelial skin cancer and melanoma. The immunosuppression used to prevent allograft rejection may be the source this via decreased immunosurveillance. composition duration independent factors for development malignancy in these patients. purpose study is evaluate regimen differences. TriNetX Research Network was study, providing access...

Titanite (CaTiSiO5) is a naturally occurring silicate phase, recently recognised as potential material for immobilization of nuclear wastes, high-end ceramic lining and optical device development. The undergoes pressure-induced structural transition (P21/c to C2/c) at ~3.5 GPa, which we confirm from density function perturbation theory. Using first principles calculations pressure-dependent par...

Refinery treatment plants produce large quantities of oily sludge during the petroleum refining processes. The hazardousness associated with disposal these wastes, make necessary development innovative technologies to handle it adequately, linked concepts circular economy and environmental sustainability. This work provides for first time a methodology deep characterization this kind wastes con...

In evaluating credit risk models, it is common to use metrics such as power curves and their associated statistics. However, power curves are not necessarily easily linked intuitively to common lending practices. Bankers often request a specific rule for defining a cut-off above which credit will be granted and below which it will be denied. In this paper we provide some quantitative insight in...

Revenue cap regulation is often combined with systematic benchmarking to reveal the managerial inefficiencies when regulating natural monopolies. One example is the European energy sector, where benchmarking methods are based on actual cost data, which are influenced by managerial inefficiency as well as operational heterogeneity. This paper demonstrates how a conditional nonparametric method, ...