In the ph 3 PACIFIC trial of pts with unresectable stage III NSCLC and no progression after concurrent CRT, D improved survival vs placebo (P), manageable safety detrimental effect on PROs. Any-grade PNS (incl. radiation PNS) was common. We report post hoc analyses assessing impact all cause, study G2+ PROs D. Pts PS 0/1 were randomized 2:1 (1–42 days CRT) to (10 mg/kg IV q2w for 12 months) or ...

Thyroid cancer ranks as the ninth most common worldwide and third in Saudi Arabia. Given thyroid cancer's high incidence, patients' quality of life (QoL) has been a concern for many years. However, no study dedicated to assessing QoL Thus, we aimed fill this gap by This cross-sectional was conducted among patients attending outpatient clinics at Diabetes Endocrinology Centre, King Fahad Special...

In the phase III CASTOR trial, daratumumab, bortezomib and dexamethasone (D-Vd) significantly extended progression-free survival compared with (Vd) alone in patients relapsed/refractory multiple myeloma (RRMM). Here, we present patient-reported outcomes (PROs) from trial. PROs were assessed using European Organisation for Research Treatment of Cancer Quality Life Questionnaire Core 30-item (EOR...

the main objective of this paper is to evaluate the effect of r&d on profitability of high -tech industries with new evidence from the iranian industries carrying four- digit codes. the structure- conduct- performance (scp) paradigm, which is relatively well known in industrial economics and in organization management, provides the theoretical construct that guides our empirical model formu...