C-fos has been reported to be one of the immediate early genes in signal transduction systems after many kinds of stresses, including ionizing radiation. Changes in c-fos expression induced by radiation therapy in tumor tissues have not yet been reported. In this study, we have attempted to determine whether c-fos expression is induced by radiotherapy in human squamous cell carcinomas of the he...

Considering current controversies regarding the health effects of low doses of ionizing radiation, study of the high background radiation areas such as Ramsar, Iran can help scientists better evaluate the validity of linear no-threshold (LNT) hypothesis. Ramsar is a coastal city in northern Iran with some areas known to have the highest levels of natural background radiation in the world. The m...

The immunofluorescence-based detection of c-H2AX is a reliable and sensitive method for quantitatively measuring DNA double-strand breaks (DSBs) in irradiated samples. Since H2AX phosphorylation is highly linear with radiation dose, this wellestablished biomarker is in current use in radiation biodosimetry. At the Center for High-Throughput Minimally Invasive Radiation Biodosimetry, we have dev...

background: radon is the second leading cause of lung cancer after smoking. in canada, the health authorities have no access to comprehensive profile of the communities built over uranium-rich micro-geological settings. the present indoor radon monitoring guideline is unable to provide an accurate identification of health hazards due to discounting several parameters of housing characteristics....

OBJECTIVES To investigate the protective effect of L-Glutamine in animals undergone to ventral radiation when the target organ is not the prostate. MATERIALS AND METHODS Wistar rats were divided into groups of 10 animals each: Controls (C), maintained under standard conditions and not exposed to radiation, Radiated group (R) undergone to abdominal radiation only and Radiated plus supplemented...

elevated amount of the free radicals due to ionizing radiation causes deteriorating damage on immune system. therefore, we made attempts to investigate the protective effect of vitamin e (vit-e), a biological antioxidant in balb/c mice, so as to find an affordable prophylactic supplementation for individuals who are at risk. several groups of mice were selected and exposed to sub-lethal g -irra...

introduction the exposure of human beings to ionizing radiation from natural sources is a continuing and inescapable feature of life on earth. for most individuals, this exposure exceeds that from all man-made sources combined. materials and methods in this study, the annual effective dose in high level environmental background radiation areas (hlebras) of northern city of ramsar in iran was de...

Ionizing radiation (IR) is a well-known carcinogen, however the mechanism of radiation induced thymic lymphoma is not well known. Moreover, an easy and effective method to protect mice from radiation induced thymic lymphoma is still unknown. Hydrogen, or H(2), is seldom regarded as an important agent in medical usage, especially as a therapeutic gas. Here in this study, we found that H(2) prote...

BACKGROUND Use of c-arm fluoroscopy is common in the operating room, outpatient clinic, and emergency department. Consequently, there is a concern regarding radiation exposure. Mini-c-arm fluoroscopes have gained popularity; however, few studies have quantified exposure during mini-c-arm imaging of a body part larger than a hand or wrist. The purpose of this study was to measure radiation expos...