Background: Currently available radioprotectors are poorly tolerated in man and the general use of aminothiols is compromised by their side effects. This study was carried out to test and compare the radioprotective potential of cimetidine and famotidine against lethally gamma irradiated NMRI mice. Materials and Methods: Adult male NMRI mice in groups of 10 were exposed to various doses of gamm...

BACKGROUND mu-Opioid receptor agonists are strong analgesics. However, their usefulness for preemptive analgesia is controversial. The authors tested antinociceptive and preemptive properties of fentanyl as a mu-opioid receptor agonist in a model of spinal nociception in vivo. METHODS C fiber-evoked potentials were recorded in the superficial laminae I-II of the rat lumbar spinal cord with gl...

This research, works with the effective Hamiltonian and the quark model. Using, the decay rates of matter-antimatter of b quark was investigated. We described the effective Hamiltonian theory which was applied to the calculation of current-current (Q1,2), QCD penguin (Q3,…,6), magnetic dipole (Q8) and electroweak penguin (Q7,…,10) decay rates. The gluonic penguin structure of hadronic decays ...

ß-lactamase activity was studied in Neisseria gonorrhoeae strains. Optimum temperature was found to be 37°C. The enzyme was inactivated at temperatures higher than 60°C, but remained active during storage at low temperatures (4°C, -30°C and -70°C) for two months. Enzyme activity was observed within a pH range of 5.8-8.0, while the optimum pH was 7.0-7.2. Addition of Ni2+, Fe2+, Fe3+, Mn2+ and p...

From June 1993 to September 1995, 132 case files of patients who received palliative radiotherapy (RT) for skeletal metastases were reviewed. Majority of the patients (75/132) was in the age range of 41-60 years. Common sites of metastases were the vertebrae (86 patients) and the pelvic bones (40 patients). The major primary tumors encountered were as follows: multiple myeloma (30), breast canc...