Mammalian DNA ligase III (LigIII) functions in both nuclear and mitochondrial DNA metabolism. In the nucleus, LigIII has functional redundancy with DNA ligase I whereas LigIII is the only mitochondrial DNA ligase and is essential for the survival of cells dependent upon oxidative respiration. The unique LigIII zinc finger (ZnF) domain is not required for catalytic activity but senses DNA strand...

in the past, rock slope stability analysis were performed either graphically or using a hand-held calculator, but nowadays there are variety of slope stability analysis which can be used according to the field condition and potential failure mode. in 2-d analysis, effect of convex and concave walls are neglected, however concave slopes are believed to be more stable than straight walls due to t...

quantification of arterial elasticity and its dependency to age is considered in this paper. we use radiofrequency (rf) signals fromcarotid artery ultasonography to evaluate this dependency. blood pressure, blood flow, and tethering to surrounding tissue are the maincauses of the motion of the carotid wall. tracking carotid artery wall motion from a series of ultrasound b‑mode images is challen...

with the growing population and density in metropolitan areas, higher tendency to live in high-rise buildings, and increasing demand for parking lots, it seems necessary to excavate soil to construct underground spaces. during excavation work, as the height of the wall increases, special care should be taken to the wall stabilization to avoid any consequent damage including extensive property d...

BACKGROUND Few published large series have described a surgical approach to maxillary skeletal reconstruction on the basis of the extent of maxillectomy. METHODS We have reviewed a 10-year experience with 38 consecutive maxillary reconstructions with respect to maxillectomy defects, reconstructive procedures, reconstructed buttresses, and functional and aesthetic outcomes. RESULTS Maxillect...

Coordination of an ambiphilic diphosphine-borane (DPB) ligand to the RhCl(CO) fragment affords two isomeric complexes. According to X-ray diffraction analysis, each complex adopts a square-pyramidal geometry with trans coordination of the two phosphine buttresses and axial RhB contacts, but the two differ in the relative orientations around the rhodium and boron centres. DFT calculations on the...

In order to adequately investigate an allegation of sexual abuse, professionals must both understand the motives of the victim, perpetrator, and victim's mother (in incest cases) to lie or tell the truth and possess the techniques for examining the child's story. Children almost never make up stories about being sexually abused. In fact victims are often revictimized in multiple ways for truthf...

Vertical ‘down grafting’ of the maxilla is routinely performed using orthotopic bone graft or heterotopic donor bone products. It is well documented that with this approach, bone grafting does not always result in a favorable stable outcome as relapse commences before complete integration of the graft. We wish to highlight the ‘down sliding’ osteotomy, first described by Reynekein 1985, whi...

We present the initial phenotypic characterization of an Arabidopsis mutation, terminal flower 1-1 (tfl1-1), that identifies a new genetic locus, TFL1. The tfl1-1 mutation causes early flowering and limits the development of the normally indeterminate inflorescence by promoting the formation of a terminal floral meristem. Inflorescence development in mutant plants often terminates with a compou...