Maternal high-fat diet consumption and obesity have been shown to program long-term obesity and lead to impaired glucose tolerance in offspring. Many rodent studies, however, use non-purified, cereal-based diets as the control for purified high-fat diets. In this study, primiparous ICR mice were fed purified control diet (10-11 kcal% from fat of lard or butter origin) and lard (45 or 60 kcal% f...

A conspicuous feature of the cirrhosis that is produced by butter yellow is the new formation of bile ducts that sprout from ducts of the larger portal spaces and penetrate between "portal units" to anastomose with liver cell columns at the periphery of these units. Hyperplasia of the liver may occur with butter yellow administration in the absence of cirrhosis or other change associated with w...

BACKGROUND AND PURPOSE There is an inverse association between dairy food consumption and the incidence of stroke in observational studies. However, it is unknown whether the relationship is causal or, if so, what components in milk are responsible for reducing the incidence of stroke. METHODS Stroke-prone spontaneously hypertensive rats were fed diets comprising amino acids, proteins from di...

Milk fats from different species of mammals are known to vary considerably in chemical composition. In early work, the butter fat constants were largely used to indicate the differences in composition. More recently, emphasis has been placed on comparisons of the component fatty acids of the various types of butter fats. The methods available for separation of the acids are not conducive to hig...

Milk fats from different species of mammals are known to vary considerably in chemical composition. In early work, the butter fat constants were largely used to indicate the differences in composition. More recently, emphasis has been placed on comparisons of the component fatty acids of the various types of butter fats. The methods available for separation of the acids are not conducive to hig...

BACKGROUND Dietary conjugated linoleic acid (CLA) is known to reduce atherosclerosis, plasma total and LDL-cholesterol concentrations, and body fat accumulation in several animal species. Of the few studies that investigated the effects of CLA supplementation in humans, all used commercially formulated oral supplements made from a mixture of CLA isomers. OBJECTIVE We compared the effects on p...

The cholesteryl ester content of plasma low density lipoproteins (LDL) in monkeys has previously been shown to be related to the rate of hepatic cholesterol secretion and cholesteryl ester content of newly secreted lipoproteins in the isolated perfused liver. In the present studies, African green monkeys were fed diets containing cholesterol and 40% of calories as either butter or safflower oil...

Butter is a readily collected, integrative and inexpensive sampling matrix for the spatial mapping of persistent organic pollutants (POPs) at the national or regional scale. As air-plant-animal transfers generally supply the POPs reaching butter lipid, this study used butter for an initial evaluation of the occurrence, levels and distribution of POPs (selected organochlorine pesticides and PCBs...

Feeding a butter-rich diet to rats induced a "hypercoagulable state," since multiple large thrombi were observed in response to injection of S. typhosa endotoxin but the same stimulus was ineffective in rats fed a corn oil-rich diet or laboratory chow. In vitro hypercoagulability was noted in blood from the butter-fed rats, the recalcification plasma clotting time (PCT) being reduced by 34 to 4...