The elimination of malignancy is the ultimate oncologic goal. Many tumors can be killed by large amounts of chemotherapy or ionizing radiation. Unfortunately, host tolerance to treatment frequently limits the extent to which these modalities can be used. Therefore, skilled use of effective but nonselective modalities is the present basis of oncology. The recent clinical interest in the use of p...

Two years ago, in an editorial [1] sparked by the revelations from PLoS Medicine and The New York Times’ intervention in litigation relating to Prempro [2], we wrote that ‘‘the story told in these documents amounts to one of the most compelling expositions ever seen of the systematic manipulation and abuse of scholarly publishing by the pharmaceutical industry and its commercial partners in the...

Software-defined radio dongles are small and inexpensive receivers well known to amateur enthusiasts. When connected an antenna, they enable monitoring of a wide range the spectrum by conditioning input signal transferring downconverted version it personal computer for software processing. Here, we employ composite two such dongles, interfaced with codes written in MATLAB GNU Radio, as measurin...

We experimentally investigate intermodal nonlinear interactions, such as Raman scattering and four wave mixing. The fiber used is a specially designed few moded fiber, which splits the degeneracy of the first mode group, leading to stable propagation of the two full vectorial modes, TM01 and TE01. For the Raman experiments pumping occur in either the fundamental mode or the two full vectorial m...