Increasing evidence showed the important role of nitric oxide (NO) in skin repair and reconstruction. In this report, we investigated the effects of NO on 2nd degree burn wound of mice with a newly developed topical NO-gel. Using regular hematoxylin&eosin staining and immunohistochemistry, we determined the effects of NO on wound closure, hair follicle regeneration, collagen deposition, angioge...

Burn patients are highly susceptible to infections due to increased exposure through wounds and impairments in a number of immune functions. Dendritic cells (DCs) are important in activation of numerous immune responses that are essential for the clearance of infections. We have found that prophylactic treatment of burn-injured mice with the DC growth factor FLT3 ligand (FL) significantly incre...

conclusions this study represented an increasing rate of mdr p. aeruginosa in burn and wound samples. efflux mexab genes were detected in all mdr and pdr strains. the p. aeruginosa strain isolated from burn cases showed higher drug resistance and pdr resistance was only noted in a burn sample. materials and methods one-hundred and fifty p. aeruginosa were isolated from burn and wound infections...

BACKGROUND In the paediatric population, pain and distress associated with burn injuries during wound care procedures remain a constant challenge. Although silver dressings are the gold standard for burn care in Australasia, very few high-level trials have been conducted that compare silver dressings to determine which will provide the best level of care clinically. Therefore, for paediatric pa...

INTRODUCTION Burn injury is a medical problem as well as a social burden on the national health services in developing countries. Trace elements have important roles in wound healing and act as antioxidants. In this study, zinc (Zn) and copper (Cu) levels in plasma of burned patients and their relationship with the burn surface area and time-related pattern are determined in the admitted patien...

BACKGROUND Burn injury is a major cause of death and disability worldwide. A domestic medication in wound healing, preventing infection and reduction of scar tissue as well as availability is still an important challenge. This study aims to evaluate the efficacy of yolk egg oil in treatment of burn wounds in rats. METHODS A standard 3rd degree burn wound was produced and the animals were divi...

according to the national institutes of health and the center for disease and prevention, it is estimated that 65 to 80 percent of the human infectious are caused by biofilms. antibiotics and drainage of purulent discharge are the main treatment measures. but in chronic infections sometimes these findings are not easy to recognize. biofilm is an extracellular polymeric conglomeration generally ...

burns are known as one of the most common forms of injury with devastating consequences. despite the discovery of several antiseptics, burn wound healing has still remained a challenge to modern medicine. herbal products seem to possess moderate efficacy with no or less toxicity and are less expensive compared to synthetic drugs. burn is a well-known disorder in iranian traditional medicine (it...

Background and Purpose: Vitamin C is administered orally or intravenously for the treatment of burn wounds. However, effects of the topical application of vitamin C remain unclear. This study aimed to evaluate the effects of topical vitamin C solution on the necrotic tissue volume of second-degree burn wounds. Methods: This clinical trial was conducted on 30 patients with second-degree burns a...

BURN PATIENT participates in a virtual-reality program to relieve the pain of his wound care at Harborview Burn Center in Seattle (above). Wearing a headset and manipulating a joystick, the patient maneuvers through the program called SnowWorld (right), which was specifically designed to ease the pain of burn victims. Studies show that virtual-reality programs are more effective than ordinary v...