Abstract Teledermatology (TD) assessment of lesions referred on the 2-week wait (2WW) pathway reduces need for in-person review, and thus facilitates increased clinical capacity. Although studies have demonstrated that TD can be cost-effective compared with a standard face-to-face (F2F) model, there is lack literature cost-effectiveness medical photography in UK 2WW skin cancer (Snoswell C, Fin...

Biotin is a water-soluble vitamin that functions as a cofactor for biotin-dependent carboxylases. The biochemical and physiological roles of biotin in brain regions have not yet been investigated sufficiently in vivo. Thus, in order to clarify the function of biotin in the brain, we herein examined biotin contents, biotinylated protein expression (e.g. holocarboxylases), and biotin-related gene...

This research aims to examine the association between a different type of income shifting incentives and auditor utilization corporate tax avoidance in Indonesia. These include multinationality, transfer pricing aggressiveness, thin capitalization, intangible assets. We analyse manufacturing companies listed Indonesia Stock Exchange during 2014 2017 replicating Taylor Richardson (2012) (2015) m...

BACKGROUND The EuroQol Group has extended the severity levels of the EQ-5D from three to five (EQ-5D-5L). There are valuation studies worldwide planned in order to convert the EQ-5D-5L health states into a single preference-based summary score based on country-specific value sets of social health status preference valuations. The EuroQol Group developed an internationally standardised EQ-5D-5L ...

The variable ordering heuristic is an important module in algorithms dedicated to solve Constraint Satisfaction Problems (CSP), while it impacts the efficiency of exploring search space and size tree. It also exploits, often implicitly, structure instances. In this paper, we propose Conflict-History Search (CHS), a dynamic adaptive for CSP solving. based on failures considers temporality these ...