Asthma is a heterogeneous disease with variable characteristics such as lung function, symptoms and control, body weight, pattern of inflammation, and response to treatment. Brittle asthma is one of clinical phenotypes of asthma with unclear pathogenic mechanisms and appropriate treatment. Analysis of 2 described cases suggests that omalizumab could be useful in the treatment of brittle allergi...

Stress corrosion experiments were performed on unidirectional ECR-glass/polymer composites with the modified polyester, epoxy and vinyl ester resins for the use in high voltage composite insulator applications. Two types of ECR-glass fibers with low and high seed counts were investigated. The stress corrosion tests were performed in nitric acid under four point bending conditions and the resist...

Abstract: It is easy for composite laminates to be damaged by relative lower velocity impact which could give rise to internal delamination that will strongly weaken the compressive strength of laminates. In order to predict the occurrence of matrix failure, the elastic-brittle behaviors of fiber-reinforced composites were modeled constitutively by an anisotropic damage model. The dynamic tensi...

Scratches are deleterious to precision optics because they can obscure and modulate incident laser light, which will increase the probability of damage to optical components. We here imitated the generation of brittle and ductile scratches during polishing process and endeavored to find out the possible influence of scratches on laser induced damage. Brittle scratches can be induced by spiking ...

Owing to a lack of microstructure, glassy materials are inherently strong but brittle, and often demonstrate extreme sensitivity to flaws. Accordingly, their macroscopic failure is often not initiated by plastic yielding, and almost always terminated by brittle fracture. Unlike conventional brittle glasses, metallic glasses are generally capable of limited plastic yielding by shear-band sliding...

Portland cement concrete (PCC) has been successful in many applications. However, since the 1960s technological investigations concerning modifications of concrete by polymeric materials have been conducted. Attention has been focused on concretes in which the continuous phase is some kind of polymeric resin and the discrete phase is some type of mineral aggregate. Such composite materials are ...

Unstable and unpredictable disease control in diabetes or asthma, with frequent hospitalisations, is frequently referred to as 'brittle'. We describe two cases of Addison's disease with recurrent hospitalisations in hypo-adrenal crises. Both patients had significant psychosocial disruption, and failure to take hydrocortisone replacement therapy was admitted in one and biochemically proven in th...

In this work, a theoretical approach is proposed for estimating the minimum and maximum reinforcement ratios hybrid glass fiber reinforced polymer (GFRP)/steel-reinforced concrete beams to prevent sudden brittle failure as well compression of before tension reinforcements. Equilibrium equations were used develop method determining GFRP/steel ratio. A ratio was also developed based on equilibriu...

Concrete is a brittle material. The lack of durability of concrete infrastructure has been a recognized concern. Research in fiber reinforced concrete (FRC) often addresses the issue of material brittleness. However, the translation of improved ductility of FRC into infrastructure durability is often overlooked. This paper explores the concept of elevating the ductility of high performance fibe...