Introduction The traumatic effects of COVID-19 pandemic is well studied in community and fragile groups. association between infection development severe mood disorders have not studied. Objectives Nonetheless the casual relation or stressor Covid-19 on chronic psychiatric illness known yet. present study aimed to investigate as a triggering factor first episode Bipolar disorder (BD) patients t...

The quality of the therapeutic relationship between psychiatric patients and their attending physicians plays a key role in treatment success. We hypothesize that mandatory treatment is negatively associated with the quality of the therapeutic relationship. In a cross-sectional study design, data on psychopathological symptom load (as captured with the Brief Psychiatric Rating Scale) and on the...

BACKGROUND The clinical efficacy of dopamine D2 receptor antagonism on the psychotic symptoms of schizophrenia has been widely demonstrated. However, most in vivo imaging studies have not been able to detect significant changes in striatal D2 receptors in schizophrenia. On the other hand, a number of studies have reported abnormalities in the cerebral cortex of schizophrenia. The aim of this st...

BACKGROUND Despite the demonstrated efficacy of clozapine in severely refractory schizophrenia, questions remain regarding its efficacy for primary negative symptoms, comparison with a moderate dose of a first-generation antipsychotic, and adverse effects during a longer-term trial. This study examined its efficacy in partially responsive, community-based patients, compared clozapine with moder...

Objective: the aim was to study psychometric properties of the Perceived Global Distress Scale (PGD) for people with severe mental illness, mainly with schizophrenia disorders. Methods: PGD is a Visual Analogue Scale included in “The Quality Star”, a minimal platform for clinical follow-up and efficiency documentation of mental health services in eight dimensions used in Sweden. Naturalistic da...

PURPOSE Only a few studies have commented on the use of atypical antipsychotics for the treatment of Borderline Personality Disorder (BPD) features, including affective dysregulation and aggression. We aimed at evaluating both efficacy and safety of quetiapine in a sample of consecutive BPD patients. GENERAL METHODS 29 BPD outpatients entered, and 23 completed, a 12 week, open-label, regime o...

OBJECTIVE Chronic arsenic poisoning (Arsenicosis) is a global health risk, and it has been reported to improve the fitness, especially in altitudinal sickness in therapeutic dose. Scarcity of systematic study on psychiatric co-morbidities in Arsenicosis motivated us to conduct this research. The aim of this study was to estimate the co-morbid psychiatric disorders in patients with arsenicosis a...