abstract background: the increase in breast cancer incidence has enhanced attention towards breast cancer risk. the aim of this study was to determine the risk of breast cancer and risk perception of women, factors that affect risk perception, and to determine differences between absolute risk and the perception of risk. methods: this cross-sectional study was carried out among 346 women whose ...

BACKGROUND Previous studies have suggested DNA methylation in blood is a potential epigenetic marker of cancer risk, but this has not been evaluated on a genome-wide scale in prospective studies for breast cancer. METHODS We measured DNA methylation at 27578 CpGs in blood samples from 298 women who developed breast cancer 0 to 5 years after enrollment in the Sister Study cohort and compared t...

Breast cancer is the most commonly diagnosed invasive cancer among women. Many factors, both genetic and non-genetic, determine a woman's risk of developing breast cancer and several breast cancer risk prediction models have been proposed. It is vitally important to risk stratify patients as there are now effective preventive strategies available. All women need to be counseled regarding health...

Breast cancer is the second major cause of deaths in women. Machine learning classification techniques can be used to increase precision diagnosis and bring it closer 100%, thus saving lives many people. This paper proposed four different models, built using combinations selected features applying five ML all models identify best model with highest accuracy. It analyzes machine techniques, name...

background: cancer/testis antigens (ctas) are members of a group of proteins which are normally expressed in testis germ cells and to a lesser extent in the ovaries. because of recent reports about their aberrant and specific expression in some tumoral tissues, they may play a role as new candidates for targeted therapy. therefore, the study of the expression pattern of these biomarkers and its...

Dysregulated expression of lncRNAs has been observed in various human complex diseases (including cancers) by recent transcriptional profiling studies, highlighting potentials of lncRNAs as biomarkers for cancer diagnosis and prognosis. Despite some efforts have been made to search for novel lncRNA signature in breast cancer, the prognostic value of lncRNAs for ER-positive breast cancer patient...

Purpose: Breast Cancer (BC) is considered as one of the most dangerous diseases, especially in women. The survivability patient a challenging task if breast cancer severe stage. It very much essential for early classification ultrasound images (BUIs) into several categories such benign (BN), malignant (MG) and normal (NL), etc. so that preventive measures can be taken accordingly at earliest. A...

background: breast cancer is the most incident cancer and the fifth cause of death due to malignancies among iranian women. a strong breast cancer patients' sense of meaning and purpose in life appears to decrease anxiety in their life. the present study has investigated the effectiveness of group logotherapy on the reduction of anxiety in women with breast cancer. methods: the research was qua...

objective(s):cytochrome p-450 1a1 is an important enzyme in the first phase of the metabolism of some carcinogens such as polycyclic aromatic hydrocarbons (pahs), as well as estrogen. the present study evaluates the existence of cyp1a1 polymorphism in a number of breast cancer samples. materials and methods: one hundred breast cancer patients and the same number of healthy controls were analyze...