OBJECTIVE Adjuvant irradiation after resection of brain metastases reduces the risk of local recurrence. Whole-brain radiation therapy can be associated with significant neurotoxicity in long-term survivors of brain metastases. This retrospective study evaluates the role of tumor bed stereotactic radiosurgery as an alternative method of irradiation after initial resection of brain metastases to...

background: to determine which radiotherapy parameters are associated with the tumor response of locally advanced non-small cell lung cancer (nsclc) patients undergoing concurrent chemoradiotherapy. materials and methods: thirty one patients with iiia/iiib nsclc underwent chemoradiotherapy with a median dose of 63 gy. on our actual treatments, we made radiotherapy planning to cover the planning...

High-grade meningiomas are rare extra-axial tumors, frequently causing brain invasion and prominent brain edema. Patients harboring high-grade meningiomas occasionally present with behavior changes. Data about frequency and prognostic importance of preoperative behavior changes in patients with high-grade meningiomas is missing. 86 patients with primary high-grade meningiomas were analyzed. Sta...

The incidence of a metastatic tumor the calvaria is uncommon, but it has considerable impact in field neurosurgery. hematogenous spread was common leiomyosarcoma. Calvaria one most uncommon locations for this type cancer. A 70-year-old man with history rhabdomyosarcoma and thyroid cancer came parietal mass that rapidly enlarged, followed by sudden hemiparesis severe cognitive impairment. Head C...

background: most patients with superficial bladder cancer whoundergo transurethral resection of bladder tumor show recurrenceof the disease. so far, there have been numerous studies on waysto decrease bladder cancer recurrence, including the intake ofvitamins and antioxidants. the goal of this study was to investigatethe effect of vitamin e on the recurrence of non‑invasive bladdercancer.method...

Brain tumors are a heterogeneous group of benign and malignant arising from the brain parenchyma its surrounding structures, with in general poor clinical outcome due to high recurrence. One underlying causes for this somber prognostic is presence tumor initiating cells (BTIC) endowed self-renewal potential, multi-lineage differentiation resistance treatment. promising therapeutic avenue target...

Over the last two decades the large volume of research involving various brain tracers has shed invaluable light on the pathophysiology of cerebral neoplasms. Yet the question remains as to how best to incorporate this newly acquired insight into the clinical context. Thallium is the most studied radiotracer with the longest track record. Many, but not all studies, show a relationship between (...

GH deficiency is common in survivors of childhood cancer, especially in those treated with radiation to the brain. The impact of GH therapy on disease recurrence has been studied in survivors of pediatric brain tumors, but few data are available on the risk of disease recurrence in survivors of other tumor types who are treated with GH. Likewise, the risk of second neoplasms (SN) associated wit...

background: microcystic adnexal tumor is a rare sclerosing variant of ductal carcinoma of eccrine sweat glands which is highly invasive. this tumor is often misdiagnosed as other benign or malignant skin lesions and improper treatment is carried on and is associated with high recurrence rate. case presentation: we reported here in a 59-years old man who underwent incisional biopsy for a ongenit...

Primary extracranial meningioma (PEM) is a very rare disease that arises outside the dural covering of brain or spinal cord. It essentially an tumor and can mimic musculoskeletal malignancies. A 74-year-old woman presented with mass on right frontotemporal scalp had been present for 2 years. Magnetic resonance imaging revealed osteolysis in frontal, temporal, sphenoid bone involvement temporali...