BACKGROUND Brain injury is a major adverse event after cardiac surgery, especially when extracorporeal circuits are used. We evaluated whether cardiopulmonary bypass (CPB) affects cerebrovascular resistance and plasma concentrations of adrenomedullin (AM), a vasoactive peptide regulating cerebral blood flow. METHODS We evaluated 50 infants (age <1 year) with congenital heart defects, matched ...

In fetuses with complex congenital heart disease (CHD), impaired brain growth and development starts in utero. A interplay between heart, brain, body placenta takes place the second third trimesters of pregnancy. Altered fetal cardiovascular hemodynamics due to differnt types CHD lead altered cerebral, placental perfusion, all factors contributing maturational delay development. Impaired cerebr...

The use of corticosteroids in cases brain tumors has become common to reduce edema. However, the can cause adrenal insufficiency (AI) if used long-term and large doses with rapid withdrawal. In pituitary macroadenoma that undergone surgery, AI may also occur. affects treatment tumor patients. Hence, is an important problem because almost all patients receive at some point course their disease. ...

BACKGROUND Cerebral perfusion can be evaluated using a computed tomography (CT) scan by intravenous bolus injection of contrast media. The purpose of this study was to investigate the value of CT perfusion (CTP) in follow-up of extracranial-intracranial (EC-IC) bypass surgery. METHODS We retrospectively reviewed pre- and postoperative CTP studies in 14 patients who received EC-IC bypass surge...

PURPOSE Hemorrhagic metastatic brain tumors are not rare, but little is known about the surgical outcome following treatment. We conducted this study to determine the result of the surgical outcome of hemorrhagic metastatic brain tumors. MATERIALS AND METHODS From July 2001 to December 2008, 21 patients underwent surgery for hemorrhagic metastatic brain tumors at our institution. 15 patients ...

Functional neurological changes after surgery combined with diffusion tensor imaging (DTI) tractography can directly provide evidence of anatomical localization of brain function. Using these techniques, a patient with dysgraphia before surgery was analyzed at our hospital in 2011. The patient showed omission of kana within sentences before surgery, which improved after surgery. The brain tumor...

The Stria Medullaris (SM) is a white-matter tract that contains afferent fibres connect the cognitive-emotional areas in forebrain to Habenula (Hb). Hb plays an important role behavioral responses reward, stress, anxiety, pain, and sleep through its action on neuromodulator systems. Fasciculus Retroflexus (FR) forms primary output of midbrain. SM, Hb, FR are part special pathway between midbrai...