We present a robust intrasubject registration method for the synergistic use of multiple neuroimaging modalities, with applications to magnetic resonance imaging (MRI), functional MRI, perfusion MRI, MR spectroscopy, and single-photon emission computed tomography (SPECT). This method allows user-friendly processing of difficult examinations (low spatial resolution, advanced pathology, motion du...

fixed myocardial defects in both stress and rest images, could be artifactual as a result of soft tissue attenuation. to increase specificity and identify the false positive results, we used gated technique to evaluate the wall motion and wall thickening as an index to differentiate real ischemic lesions from artifactual defects. 93 patients were studied. in 46 patients (48.8%) fixed perfusion ...

UNLABELLED Myocardial perfusion imaging with SPECT (SPECT-MPI) and 64-slice CT angiography (CTA) are both established techniques for the noninvasive evaluation of coronary artery disease (CAD). Three-dimensional (3D) SPECT/CT image fusion may offer an incremental diagnostic value by integrating both sets of information. We report our first clinical experiences with fused 3D SPECT/CT in CAD pati...

With the use of perfusion tracers, in vivo examination of the regional cerebral blood flow in cats can be performed with single photon emission computed tomography (SPECT). Reliable perfusion data of normal, healthy cats are necessary for future clinical studies or other research use. Therefore, this dataset of the regional perfusion pattern of the normal feline brain was created. Twelve cats w...

UNLABELLED This study examined the relationship between the severity of aphasia and regional cerebral perfusion on brain SPECT using statistical parametric mapping (SPM) and a statistical probabilistic anatomic map (SPAM) in patients with a striatocapsular infarction (SCI) along with the other clinical and imaging findings. METHODS The subjects were 16 right-handed Korean-speaking patients wi...

BACKGROUND An increase in the EEG upper/low α power ratio has been associated with mild cognitive impairment (MCI) due to Alzheimer's disease (AD) and to the atrophy of temporoparietal brain areas. Subjects with a higher α3/α2 frequency power ratio showed lower brain perfusion than in the low α3/α2 group. The two groups show significantly different hippocampal volumes and correlation with θ fre...

Objective—To determine whether myocardial contrast echocardiography (MCE) following intravenous injection of perfluorocarbon microbubbles permits identification of resting myocardial perfusion abnormalities in patients who have had a previous myocardial infarction. Patients and interventions—22 patients (mean (SD) age 66 (11) years) underwent MCE after intravenous injection of NC100100, a novel...