INTRODUCTION Previous studies have shown that obese individuals have reduced natriuretic peptide levels. But conflicting data exist on the relation of natriuretic peptide levels to other metabolic risk factors. MATERIAL AND METHODS We investigated the relationship between plasma N-terminal pro-B-type natriuretic peptide levels (NT-proBNP) and metabolic syndrome (MetS) and metabolic risk facto...

A randomized, controlled trial of baroreflex activation therapy (BAT) in patients with heart failure and reduced ejection fraction demonstrated that BAT was safe significantly improved patient-centered symptomatic outcomes, increasing exercise capacity, improving quality life , decreasing n-terminal pro B-type natriuretic peptide (NT-proBNP), functional class. approved by the FDA for improvemen...

C ardiovascular disease is the most frequent cause of death in patients with diabetes (1). It is difficult to evaluate the cardiovascular status of patients with diabetes because of complex symptomology, evidence of silent ischemia, and subclinical cardiac disease. Brain (B-type) natriuretic peptide (BNP) and the NH2terminal fragment of its prohormone (NT-proBNP) are novel biomarkers, which are...

Brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP) are novel natriuretic peptides, originally isolated from porcine brain. Similar to atrial natriuretic peptide (ANP), BNP is also synthesized in and secreted from cardiocytes, but CNP is not expressed at significant levels in normal adult myocardium. Previous studies have indicated that the serum level and ventricular expressio...

BACKGROUND Elevated natriuretic peptide levels in asymptomatic individuals without heart failure are associated with increased risk of adverse cardiovascular outcomes and may reflect subclinical cardiac dysfunction. METHODS In a sample of 313 asymptomatic individuals (51% women, mean age 61 years) with hypertension and diastolic dysfunction, we examined the association of plasma N-terminal pr...

AIMS In women with congenital heart disease (CHD), cardiovascular complications during pregnancy are common, but the risk assessment of these patients remains difficult. This study sought to determine the independent role of N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in addition to other parameters in predicting adverse cardiovascular events during pregnancy in women with CHD....

R ecurrent and lengthy hospitalisation is common in patients with heart failure and accounts for much of the treatment cost. This has led to interventions aimed at reducing hospitalisation, but identifying patients at risk of hospitalisation is difficult using traditional risk factors. Evidence accumulates for the value of brain natriuretic peptide (BNP) and N-terminal brain natriuretic peptide...

UNLABELLED To evaluate the capability of impedance cardiography (ICG) in reflecting the cardiac functions of acute myocardial infarction (AMI) patients. METHODS 99 inpatients with initial AMI were recruited. Venous blood was obtained for detection of N-terminal brain-type natriuretic peptide (NT-proBNP), B-Type natriuretic peptide (BNP) and c troponin-T (cTnT) followed by ICG. Thorax fluid ca...

Current European guidelines recommend periodic risk assessment for patients with pulmonary arterial hypertension (PAH). The aim of our study was to determine the association between the number of low-risk criteria achieved within 1 year of diagnosis and long-term prognosis.Incident patients with idiopathic, heritable and drug-induced PAH between 2006 and 2016 were analysed. The number of low-ri...