نتایج جستجو برای: brain mass

تعداد نتایج: 936119  

Journal: :Journal of proteome research 2012
Xiaozhe Zhang Filomena Petruzziello Fabio Zani Laetitia Fouillen Per E Andren Giovanni Solinas Gregor Rainer

Mass spectrometry-based neuropeptidomics is one of the most powerful approaches for identification of endogenous neuropeptides in the brain. Until now, however, the identification rate of neuropeptides in neuropeptidomics is relatively low and this severely restricts insights into their biological function. In the present study, we developed a high accuracy mass spectrometry-based approach to e...

2009
Diana K. Sarko Kenneth C. Catania Duncan B. Leitch Jon H. Kaas Suzana Herculano-Houzel

Insectivores represent extremes in mammalian body size and brain size, retaining various "primitive" morphological characteristics, and some species of Insectivora are thought to share similarities with small-bodied ancestral eutherians. This raises the possibility that insectivore brains differ from other taxa, including rodents and primates, in cellular scaling properties. Here we examine the...

Journal: :Human molecular genetics 2013
Melkaye G Melka Jesse Gillis Manon Bernard Michal Abrahamowicz M Mallar Chakravarty Gabriel T Leonard Michel Perron Louis Richer Suzanne Veillette Tobias Banaschewski Gareth J Barker Christian Büchel Patricia Conrod Herta Flor Andreas Heinz Hugh Garavan Rüdiger Brühl Karl Mann Eric Artiges Anbarasu Lourdusamy Mark Lathrop Eva Loth Yannick Schwartz Vincent Frouin Marcella Rietschel Michael N Smolka Andreas Ströhle Jürgen Gallinat Maren Struve Eva Lattka Melanie Waldenberger Gunter Schumann Paul Pavlidis Daniel Gaudet Tomás Paus Zdenka Pausova

Genetic variations in fat mass- and obesity (FTO)-associated gene, a well-replicated gene locus of obesity, appear to be associated also with reduced regional brain volumes in elderly. Here, we examined whether FTO is associated with total brain volume in adolescence, thus exploring possible developmental effects of FTO. We studied a population-based sample of 598 adolescents recruited from the...

Journal: :Archives of neurology 2010
Jeffrey M Burns David K Johnson Amber Watts Russell H Swerdlow William M Brooks

OBJECTIVE To examine body composition in individuals with early AD and without dementia and its relation to cognition and brain volume. DESIGN Cross-sectional case-control study. PARTICIPANTS Individuals without dementia (Clinical Dementia Rating, 0; n = 70) and with early-stage AD (Clinical Dementia Rating, 0.5 or 1; n = 70) in the Alzheimer and Memory Program at the University of Kansas S...

2011
Simone van de Sande-Lee Fabrício R.S. Pereira Dennys E. Cintra Paula T. Fernandes Adilson R. Cardoso Célia R. Garlipp Eliton A. Chaim Jose C. Pareja Bruno Geloneze Li Min Li Fernando Cendes Licio A. Velloso

OBJECTIVE Inflammation and dysfunction of the hypothalamus are common features of experimental obesity. However, it is unknown whether obesity and massive loss of body mass can modify the immunologic status or the functional activity of the human brain. Therefore, the aim of this study was to determine the effect of body mass reduction on brain functionality. RESEARCH DESIGN AND METHODS In hu...

Journal: :Journal of nutritional science and vitaminology 2013
Satomi Oshima Sakiho Miyauchi Meiko Asaka Hiroshi Kawano Motoko Taguchi Suguru Torii Mitsuru Higuchi

We have previously shown that resting energy expenditure (REE) adjusted by fat-free mass (FFM) in male college athletes remains consistent regardless of FFM. The FFM comprises internal organs with high metabolic activity, such as liver and brain, which account for 60 to 80% of REE in adults. The purpose of the present study is to examine the contribution of internal organs to the REE of the FFM...

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