We developed two techniques to address 3D volume parameterization and deformation mapping problems that arise in medical imaging [1]. The first algorithm finds a harmonic map from a 3-manifold to a 3D solid sphere and the second is a novel sphere carving algorithm which calculates the simplicial decomposition of a complex 3D image volume while preserving its surface topology. In this paper, we ...

Mapping mammalian synaptic connectivity has long been an important goal of neuroscience because knowing how neurons and brain areas are connected underpins an understanding of brain function. Meeting this goal requires advanced techniques with single synapse resolution and large-scale capacity, especially at multiple scales tethering the meso- and micro-scale connectome. Among several advanced ...

The development of functional mapping techniques gives neurosurgeons many options for preoperative planning. Integrating functional and anatomic data can inform patient selection and surgical planning and makes functional mapping more accessible than when only invasive studies were available. However, the applications of functional mapping to neurosurgical patients are still evolving. Functiona...

Optical imaging of intrinsic signals is widely used for high-resolution brain mapping in various animal species. A new approach using continuous data acquisition and Fourier decomposition of the signal allows for much faster mapping, opening up the possibility of applying this method to new experimental questions.

The mouse model is an important research tool in neurosciences to examine brain function and diseases with genetic perturbation in different brain regions. However, the limited techniques to map activated brain regions under specific experimental manipulations has been a drawback of the mouse model compared to human functional brain mapping. Here, we present a functional brain mapping method fo...

Research derived from non-invasive brain imaging modalities has been used to explore the spatial and temporal organization of the neural systems supporting human behavior and causing brain disorders. Imaging modalities of interest include positron emission tomography, event-related potentials, electro-and magnetoencephalography, and magnetic resonance imaging (MRI). In this talk, we will presen...

recent advances in brain and cognitive science studies have revolutionized concepts in neural dynamics, regulating mechanisms, coding systems and information processing networks which govern our function and behavior. hidden aspects of neurological and psychiatric diseases are being understood and hopes for their treatment are emerging. although the two comprehensive mega-projects on brain mapp...

This review intends to begin to build a bridge between our understanding of the effect of motor rehabilitation and brain plasticity on recovery after hemiparetic stroke. It discusses the impact of intensive post-stroke motor rehabilitation on motor recovery. This is followed by an overview of our current understanding, based on human brain mapping technologies, of brain plasticity underlying sp...

Pre-operative determination of the dominant hemisphere for speech and speech associated sensory and motor regions has been of great interest for the neurological surgeons. This dilemma has been of at most importance, but difficult to achieve, requiring either invasive (Wada test) or non-invasive methods (Brain Mapping). In the present study we have employed functional Magnetic Resonance Imaging...

The aim of this study is to provide a precise mapping of five ACT-R modules on the brain. While there exists a predefined mapping between ACT-R modules and brain regions (e.g., Anderson et al., 2007), these regions are relatively crude (cubes of ~12×12×12mm) and serve in principle only as indicators of module activity. Previously, we have shown that an analysis method called model-based fMRI ca...