Gangliogliomas (GG) are mixed glioneuronal tumors of the central nervous system (CNS), occurring mostly in the pediatric population, with common sites being temporal lobes and less commonly in the frontal and parietal lobes. We report a case of a 7-year-old child who presented with bilateral visual defects for 6 months. Magnetic resonance imaging (MRI) of the brain revealed an intensely enhanci...

Tuberous sclerosis complex is a multisystem genetic syndrome often affecting the central nervous system. The purpose of the current study was to identify topographical patterns in the distribution specific to epileptogenic (n = 37) and nonepileptogenic (n = 544) tubers throughout the brain for a cohort of 23 tuberous sclerosis complex patients with a history of seizures. Tubers localized to the...

BACKGROUND AND PURPOSE The m.3243A>G mutation is the most common pathogenic mutation in mtDNA; tissues with high dependence on aerobic energy metabolism, such as the brain, heart, and skeletal muscle, are most affected by the ensuing mitochondrial dysfunction. We hypothesized that the m.3243A>G mutation manifests as disturbances in white matter microstructural integrity and volumetric changes i...

Background: Rat prostate gland which is used in various investigation has considerable morphological differences with other mammals. There are few reports about its structure. So, this study was carried on for determining of histomorphological structure of rat prostate. Materials and Methods: Five healthy adult male rats with average weight 20 ± 180 g and approximately 3 - 3.5 months age were s...

Introduction: The authors present a review article on temporal lobe epilepsy in childhood. Methods: We performed a search in the literature. Results: The main etiologies of temporal lobe epilepsy in childhood are developmental tumors and focal cortical displasia, besides temporal medial sclerosis. The clinical features may be variable particularly in children younger than six years of age. Epil...

THYROID PHYSIOLOGY The thyroid gland lies inferior to the thyroid cartilage and is composed of 2 lobes that lie on either side of the trachea (Figure 1). The lobes are joined by a small band of tissue called the isthmus. Normally not visible on inspection, the thyroid gland can be palpated during swallowing when it is upwardly displaced. Thyroid tissue is highly vascular and is composed of foll...

Anesthetic agents are neurotropic drugs able to induce dramatic alterations in the thalamo-cortical system, promoting a drastic reduction in awareness and level of consciousness. There is experimental evidence that general anesthesia impacts large scale functional networks leading to alterations in the brain state. However, the way anesthetics affect the structure assumed by functional connecti...

Several studies have been carried out to verify neural plasticity and the language process in deaf individuals. However, further investigations regarding intrinsic brain organization on functional structural networks derived from congenital deafness are still an open question. The objective of this study was investigate main differences manifested congenitally individuals, concerning resting-st...

Objective: The present study aims to investigate the effect of emotions (negative and positive affects) and gender on the activity of different brain regions and their relationship with personality traits of extraversion, introversion, neuroticism, and stability. Methods: The study participants were 33 right-handed volunteer undergraduate students (17 males and 16 females). Our stimuli were tw...

BACKGROUND Dementia with Lewy bodies (DLB) is the second most frequent diagnosis of progressive degenerative dementia in older people. Delusions are common features in DLB and, among them, Capgras syndrome represents the most frequent disturbance, characterized by the recurrent and transient belief that a familiar person, often a close family member or caregiver, has been replaced by an identic...