A growing field of studies is focusing on the microbiota-gut-brain axis in order to better understand bidirectional communication pathways between gut bacteria and CNS. The pathophysiology neurological disorders including Alzheimer's disease autism has been attributed dysregulation gut-brain axis. Fecal microbiota transplantation method transferring faeces from a healthy donor into intestine re...

Three neurodegenerative disorders- Alzheimer’s dementia (ALZ), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS)- share a common feature in their pathogenesis: evidence of mitochondrial dysfunction reactive oxygen stress. Their pathologic classifications are based on the findings at autopsy patterns protein aggregates neurons glial cells. This pathology supports concept that neur...

Dementia is one of the age related mental problems and a characteristic symptom of various neurodegenerative disorders including Alzheimer’s disease. Desmodium gangeticum DC. (Leguminosae) is widely used in Ayurveda for treating various neurological disorders. In the present study, the effectiveness of aqueous extract of D. gangeticum in attenuating scopolamine-induced amnesia in mice was inves...

neurofibromatosis type 2 is an inherited disease. the main manifestation of the disease is the development of symmetric, non-malignant brain tumors in the region of the cranial nerve viii usually as schwannoma. we report here a 20-year-old woman with primary intracranial malignant nerve sheath tumor located in the left cerebellopontine angle. histologically, the tumor showed malignant spindle c...

introduction: ms disease destroys the myelin of the central nervous system. ms causing damage to the myelin sheath of the brain and the spinal cord. the mechanism is hurt by the immune system .and disruption of myelin producing cells or disconnect interconnected processes by disconnect inner white. ms is an autoimmune disease when leukocyte antigen system varies autoimmune disease like ms sprea...

background: parkinson's disease is one of the prevalent degenerative diseases of the neural system. oxidative stress, which has been recognized as the most important factor of parkinson's disease, plays a main role in the death of neurons in this disease. antioxidants have a proved role in the prevention of oxidative stress. objective: considering the presence of evidence regarding antioxidant ...

ae is a serious medical condition in which the immune system attacks the brain, impairing function. with rapid diagnosis and appropriate treatment, many patients recover most or all functions. however, not all patients experience full recovery; with approximately 6% mortality and other patients who never regain significant brain and/or bodily functions. autoimmune encephalitis can produce a wid...

introduction: alzheimer’s disease (ad) is an age-related neurodegenerative disease, which impairs memory and cognitive function. walnuts are a dietary source of polyphenols, antioxidants and other compounds with health beneficial effects. these characteristic of walnuts make them perfect candidates for evaluation of their possible effects on neurodegenerative diseases. therefore the present stu...