نتایج جستجو برای: brachial index carotid intima media thickness diabetes complications

تعداد نتایج: 1227349  

2011
Henrik Reinhard Niels Wiinberg Peter R Hansen Andreas Kjær Claus L Petersen Kaj Winther Hans-Henrik Parving Peter Rossing Peter K Jacobsen

UNLABELLED Intensive multifactorial treatment aimed at cardiovascular (CV) risk factor reduction in type 2 diabetic patients with microalbuminuria can diminish fatal and non-fatal CV. Plasma N-terminal (NT)-proBNP predicts CV mortality in diabetic patients but the utility of P-NT-proBNP in screening for atherosclerosis is unclear. We examined the interrelationship between P-NT-proBNP, presence ...

Journal: :Circulation. Cardiovascular genetics 2015
Marco Dauriz Bianca C Porneala Xiuqing Guo Lawrence F Bielak Patricia A Peyser Nefertiti H Durant Mercedes R Carnethon Riccardo C Bonadonna Enzo Bonora Donald W Bowden Jose C Florez Myriam Fornage Marie-France Hivert David R Jacobs Edmond K Kabagambe Cora E Lewis Joanne M Murabito Laura J Rasmussen-Torvik Stephen S Rich Jason L Vassy Jie Yao Jeffrey J Carr Sharon L R Kardia David Siscovick Christopher J O'Donnell Jerome I Rotter Josée Dupuis James B Meigs

BACKGROUND Type 2 diabetes mellitus (T2D) and cardiovascular disease share risk factors and subclinical atherosclerosis (SCA) predicts events in those with and without diabetes mellitus. T2D genetic risk may predict both T2D and SCA. We hypothesized that greater T2D genetic risk is associated with higher extent of SCA. METHODS AND RESULTS In a cross-sectional analysis, including ≤9210 Europea...

2009
Nadja Chumaeva Mirka Hintsanen Niklas Ravaja Markus Juonala Olli T. Raitakari Liisa Keltikangas-Järvinen

This study aims to explore the interactive effect of vital exhaustion (VE) and endothelial dysfunction on preclinical atherosclerosis, assessed by carotid intima-media thickness (IMT). Furthermore, interaction between VE and carotid elasticity is examined. Participants were 1,596 young healthy adults from the Cardiovascular Risk in Young Finns study. Endothelial dysfunction was measured by brac...

Journal: :Journal of atherosclerosis and thrombosis 2013
Michiaki Miyamoto Kazuhiko Kotani Kenta Okada Akihiko Ando Hideyuki Hasegawa Hiroshi Kanai Shun Ishibashi Toshiyuki Yamada Nobuyuki Taniguchi

AIM The aim of this study was to investigate the relationship between atherosclerotic manifestations and brachial and radial arterial wall elasticity (AWE) measured using the phased tracking method in patients with type 2 diabetes mellitus (T2DM). METHODS This study included T2DM patients (n= 220, mean age 59 years) without a history of stroke or coronary artery disease. The brachial AWE, rad...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2012
Taisto Sarkola Cedric Manlhiot Cameron Slorach Timothy J Bradley Wei Hui Luc Mertens Andrew Redington Edgar Jaeggi

OBJECTIVE To develop a normative data set and to study the relationship among arterial structure, different anthropometric measures, blood pressure, and arterial function during healthy childhood using very-high-resolution ultrasound (25-55 MHz). METHODS AND RESULTS In 135 healthy children between 0 and 18 years of age, we assessed the structure of the carotid arteries, larger peripheral arte...

2017
Jinyoung Shin Joo Hyun Park Yun Mi Song Kayoung Lee Joohon Sung

Bone mineral density (BMD) has been suggested to be associated with atherosclerosis. In the present study, we evaluated the association between lumbar BMD and the segments of carotid intima-media thickness (CIMT), a surrogate marker of subclinical atherosclerosis, in Korean adults, with consideration of sex and menopause status. Among 1,679 Korean adults who enrolled in a Healthy Twin Study, 72...

Journal: :American journal of epidemiology 2009
Alain G Bertoni Melicia C Whitt-Glover Hyoju Chung Katherine Y Le R Graham Barr Mahadevappa Mahesh Nancy S Jenny Gregory L Burke David R Jacobs

Prior reports regarding the association between physical activity and subclinical cardiovascular disease have not been consistent. The authors assessed physical activity and walking pace via questionnaire among 6,482 US adults aged 45-84 years without prior clinical cardiovascular disease participating in the Multi-Ethnic Study of Atherosclerosis from 2000 to 2002. Ankle-brachial index (ABI), c...

Journal: :Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 2012
Selen Yurdakul Vefa Aslı Erdemir Özlem Yıldırımtürk Mehmet Salih Gürel Saide Aytekin

OBJECTIVES Behcet's disease (BD) is a chronic inflammatory disease characterized by recurrent oral and genital ulcerations and ocular lesions. This multisystemic disorder primarily affects the vascular system. In the present study, we aimed to evaluate vascular endothelial function in patients with Behcet' s disease without vascular involvement. STUDY DESIGN We studied 40 patients with BD (44...

Journal: :Stroke 2004
Umberto Paradossi Enrica Ciofini Aldo Clerico Nicoletta Botto Andrea Biagini Maria Giovanna Colombo

BACKGROUND AND PURPOSE To assess the role of the endothelial nitric oxide synthase (eNOS) gene variants as risk factors for early atherosclerosis, we sought to investigate whether two polymorphisms located in the exon 7 (Glu298-->Asp) and in the promoter region (T-786-->C) of the eNOS gene were associated with functional changes in the endothelium and carotid intima-media thickness (IMT). MET...

2008
Seon Mi Jin Chung Il Noh Sei Won Yang Eun Jung Bae Choong Ho Shin Hae Rim Chung You Yeh Kim Yong Soo Yun

We examined whether alterations in vascular endothelial function and early structural changes in atherosclerosis are associated with microvascular complications in patients with type 1 diabetes mellitus (DM). Flow-mediated dilation (FMD) of the brachial artery and carotid intima-media thickness (IMT) measurement were performed in 70 young adults (aged 19 to 35 yr), 48 with type 1 DM, and 22 nor...

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