INTRODUCTION With varying and uncertain etiologies, avascular necrosis (AVN) of the femoral head is a degenerative disease that usually leads to hip joint destruction. The pathology of osteonecrosis is initiated by an ischemic event resulting in bone and marrow necrosis, inflammation, infarction of the lesion by fibrous scar tissue, stress fractures in the weakened subchondral bone, and collaps...

BackgroundThe present review study provides specific evidence to assess the impact of distraction techniques and hypnosis on the pain of bone marrow aspiration in children.Materials and MethodsThis review study aimed to determine the effects of distraction techniques and hypnosis on the controlling pain of bone marrow aspiration in children. Internal databases (SID, Magiran, IranMedex and Irand...

The optimal salvage therapy for patients with relapsed Burkitt lymphoma is unknown. Bone marrow necrosis is an underreported (<1% of bone marrow failures). Numb chin syndrome is another rare syndrome associated with aggressive malignancies. Survival of these syndromes is dictated by the underlying disease and is usually dismal. Our 35-year-old patient experienced an early relapse of Burkitt lym...

Murine bone marrow cells with lineage phenotypes (Lin)Sca-l+c-kit+ and Lin-Sca-l-c-kit+ cells represent primitive hematopoietic stem cells (HSCs) and committed hematopoietic progenitor cells, respectively. The number of Lin-Seal’c-kit’ HSCs in bone marrow was significantly increased in tumor necrosis factor (TNF) receptor p55-deficient (TNFR55-l-l mice compared with the TNF-R55+/+ wild-type mic...

The present study was performed to investigate the effect of 0-endorphin on macrophage colony-stimulating factor (MCSF)-induced differentiation of macrophages from bone marrow cells in a semisolid culture system. 0-endorphin increased the number of macrophage colonies when bone marrow cells were cultured in the presence of M-CSF plus lipopolysaccharide (LPS). This was not the case with LPSunres...

The treatment of bone a vascular necrosis is a big challenge considering the youthfulness of the patients involved by necrosis in sickle cell disease and the importance of the generated disability. A vascular osteonecrosis is an epiphysis pathology which could be treated by joint replacement with success, however, multiple surgical procedures are mostly necessary during the patient's life with ...

An unbiased cDNA expression phage library derived from bone-marrow endothelial cells was used to identify novel surface adhesion molecules that might participate in metastasis. Herein we report that reticulocalbin 1 (RCN1) is a cell surface-associated protein on both endothelial (EC) and prostate cancer (PCa) cell lines. RCN1 is an H/KDEL protein with six EF-hand, calcium-binding motifs, found ...

Objective(s):To study the effect of low-frequency vibration on bone marrow stromal cell differentiation and potential bone repair in vivo. Materials and Methods:Forty New Zealand rabbits were randomly divided into five groups with eight rabbits in each group. For each group, bone defects were generated in the left humerus of four rabbits, and in the right humerus of the other four rabbits. To t...

Origin to Blood Vessel Formation To the Editor: Crosby et al1 noted in their report that the recruitment of bone marrow–derived endothelial progenitor cells to newly forming blood vessels might have been hitherto overlooked. Postulated already a century ago,2 there is now ample evidence for a close association between blood progenitor cells and angiogenesis3 and the existence of a hemangioblast...

AIMS To report the first eight bone marrow necrosis (BMN) cases related to paracoccidioidomycosis (PCM) from patient autopsies with well-documented bone marrow (BM) histology and cytology. METHODS AND RESULTS A retrospective evaluation was performed on BM specimens from eight autopsied patients from Botucatu University Hospital with PCM-related BMN. Relevant BMN literature was searched and an...