Bone marrow biopsy (BMB) examination is the gold standard for staging of lymphoma which interpreted along with other clinical, laboratory and radiological investigations. This study aimed to evaluate various patterns BMB infiltration by lymphomas include Hodgkin Non usefulness compared bone aspiration (BMA). : In a period three years, there were 212 cases showed in marrow. We assessed periphera...

LCH is a disease of abnormal clonal proliferation langerhans cell the bone marrow derived monocyte-macrophage lineage. Cells with characteristic coffee bean / grooved indented nuclei background histiocytes, lymphocytes, eosinophils and other inflammatory cells are seen. Clinical presentation varies from unifocal unisystem to multifocal multisystem. We present rare case multisystem involving hig...

PURPOSE To report on a 19-year-old man with 'spontaneous' periocular hemorrhage and macrohematuria as the first signs of a bone-marrow-infiltrating rhabdomyosarcoma of the left superior rectus muscle. PROCEDURES Clinical eye examination, magnetic resonance imaging, laboratory workup and bone marrow biopsy were performed. RESULTS Magnetic resonance imaging showed a mass lesion in the left su...

We have recently demonstrated that IgD(hi) B cells can occupy an extravascular perisinusoidal niche in the bone marrow in addition to the well-established follicular niche in conventional secondary lymphoid organs. The spleen has long been considered to be the site at which newly formed B lymphocytes mature into IgD(hi) naive recirculating B cells, but the existence of mutant mice that have sel...

There was a concern on Mycobacterium tuberculosis spreading to the bone marrow, when it was applied on tuberculous spine infection. This research aimed to study the probability of using autologous bone marrow as a source of mesenchymal stem cell for patients with tuberculous spondylitis. As many as nine patients with tuberculous spondylitis were used as samples. During the procedure, the verteb...

AIMS To describe the histological appearances of bone marrow infiltrated with rhabdomyosarcoma at presentation and to determine their value in establishing the diagnosis. METHODS Patients presenting over seven years in the northern health region of England with rhabdomyosarcoma were studied. Bone marrow aspirates and trephine biopsy specimens taken at presentation were examined. RESULTS Sev...

Bone marrow examination of a patient chromosome in the previously aneuploid with a myeloproliferative disorder recell line (45,XX,-6,-22,+Ph’). This case vealed monosomy for chromosome No. 6 differs from those previously published in (45,XX,-6). Two months later, during that the Ph’ chromosome appeared de blastic crisis, reinvestigation of the bone novo during the development of frank marrow sh...

Bone marrow examination of a patient with a myeloproliferative disorder revealed monosomy for chromosome No. 6 (45,XX,-6). Two months later, during blastic crisis, reinvestigation of the bone marrow showed the presence of the Ph-1 chromosome in the previously aneuploid cell line (45,XX,-6,-22,+Ph-1). This case differs from those previously published in that the Ph-1 chromosome appeared de novo ...

Correspondence: Dr Abhimanyu Jha, MD, Associate Professor, Maharajgunj Medical Campus, Tribhuvan Univeristy, Institute of Medicine, Maharajgunj, Kathmandu, Nepal. Email: [email protected] Background: Pyrexia of unknown origin is a common diagnostic dilemma. Series of diagnostic modalities are required to arrive at diagnosis. Bone marrow examination is one of the common tests implicated in ...