This is an observational, longitudinal and retrospective study of a group of patients with moderate to severe plaque psoriasis whom had been treated with efaluzimab (1mg/Kg/week) for up to 20 weeks. Nevertheless, first dose of 0.7 mg/kg was given. The efficacy of the drug was evaluated by measuring the psoriasis area and severity index (PASI), the body surface area (BSA) and index of the qualit...

There are no direct comparison data between infliximab and entanercept in the treatment of psoriasis. This study was a mult icenter, randomised control trial done in the Netherlands to compare the efficacy, outcome of etanercept vs. infliximab in the management of moderate to severe chronic plaque psoriasis. Patients (age 1875 years old) with Psoriasis Area and Severity Index (PASI) ≥10 and/or ...

Methods We performed a retrospective review of patients late after Fontan operation who underwent CMR measurement of APC flow at our institution from 2003 through 2009. APC flow was quantified as either aortic flow minus total caval flow or aortic flow minus sum of branch pulmonary artery flow, and was indexed to body surface area (BSA). Patients with a patent fenestration or baffle leak were e...

The purpose of the present study was to examine the effects of different types of personal cooling equipments (PCE) on the alleviation of heat strain during red pepper harvest simulated in a climatic chamber. The experiment consisted of eight conditions: 1) Control, 2) Neck cooling scarf A with a cooling area of 68 cm2, 3) Neck cooling scarf B (cooling area 154 cm2), 4) Brimmed hat with a froze...

Forty-two patients, 16-60 years old, with a diagnosis of acute or chronic plaque-type psoriasis that involved at least 10% of their body surface area (BSA) were included in the study. Patients with alternative forms of psoriasis or psoriatic arthritis or who were pregnant or had a contraindication to atorvastatin were excluded. Patients were randomized into either the placebo group or the oral ...

Background Normalised left ventricular mass (LVM) is a powerful prognostic tool. Traditionally, normalising has been achieved by indexing LVM to body surface area (BSA). A recent ‘Multiethnic Study of Atherosclerosis’ (MESA) sub-study demonstrated indexing LVM to height is more sensitive at identifying left ventricular hypertrophy (LVH) associated with cardiovascular events and all-cause death....

Atopic dermatitis (AD), the most common chronic inflammatory Background skin disease, is evolving as a systemic disease, and associated systemic inflammation is possibly linked to increases in cardiovascular disease. : We assessed levels of the inflammatory marker CRP in 59 patients Methods with moderate-to-severe AD compared to matched healthy controls, and to determine correlation with skin d...

End stage renal disease is a major health problem for Australian Aborigines and African Americans. Abnormally enlarged glomeruli are commonly observed in biopsies from Aborigines and African Americans and may represent a compensatory hypertrophic response to reduced nephron endowment. We have commenced a study examining glomerular number and size, and their associations in Australian Aborigines...

Methods A total of 25 children (median age of onset 14,2 months (range, 0 mth–12ys) diagnosed with mastocytosis have been studied. Patients were classified according to the type of skin lesions following the WHO classification. Mastocytosis-related symptoms and data on specific triggering factors were systematically recorded for 3 years after diagnosis. Severity was graded according to standard...

Background Increased left atrial volume index (LAVI) has been shown to be an independent predictor of hard cardiovascular events. It can be determined by calculating left atrial (LA) volume through the use of either Simpson’s method or area-length method and indexing it to body surface area (BSA). Although there is no standardized method of calculating LA volume using Cardiac Magnetic Resonance...