The periodontal pathogen Porphyromonas gingivalis requires porphyrin supplementation for growth. Previously, in order to inhibit P. gingivalis growth, we synthesised very effective 'Trojan horse' ester and amide-linked deuterporphyrin-nitroimidazole (DPIX-Nim) adducts that exploited this requirement to transport metronidazole-derived antibiotics with excellent antimicrobial selectivity and reco...

The long PN code in a Binary Offset Carrier (BOC) modulated signal has a higher rate than the GPS C/A code, which makes the acquisition process in the new global navigation satellite system (GNSS) much more complex. To achieve a fast acquisition of the GNSS signal with a reduced number of correlators and low computational complexity, a two-stage deterministic compressed (DS) GNSS acquisition te...

This study aims to investigate the effect of good corporate governance (GCG) on sustainability performance (CSP) using Triple Bottom Line (TBL) approach in a two-tier GCG system. is measured by size and education background board commissioners (BoC) top management team (TMT). CSP consists economic, social, environment performance. As many as 117 sample data were collected from financial stateme...

Enantiopure 2-(tributylstannyl)pyrrolidine hydroiodide may be prepared in excellent yield by TMSI treatment of the corresponding N-Boc compound, which is in turn prepared by asymmetric deprotonation (s-BuLi.sparteine) and stannylation, as described in the literature. Crystals of the hydroiodide salt suitable for X-ray analysis were obtained, and although there is some disorder about the butyl g...

This study seeks to empirically evaluate the influence of Return on Assets (ROA) and Net Profit Margin (NPM) stock prices that are moderated by size board commissioners (BoC). An archival using Moderated Regression Analysis (MRA) technique was conducted consumer goods businesses listed Indonesia Stock Exchange (IDX) for years 2015 through 2019. The purposive sampling method used compile a sampl...

Tetrahydropyranylation of alcohols and phenols, acetylation of aldehydes and N-Boc protection of amines are efficiently catalyzed by melamine trisulfonic acid (MTSA). All reactions were performed at room temperature in good to high yields.

Tetrahydropyranylation of alcohols and phenols, acetylation of aldehydes and N-Boc protection of amines are efficiently catalyzed by melamine trisulfonic acid (MTSA). All reactions were performed at room temperature in good to high yields.

Isocyanide-based multicomponent reactions (IMCR) are by far the most versatile reactions that can construct relatively complex molecules by one-pot synthesis. More importantly, the development of post IMCR modifications significantly improves the scaffold's diversity. Here, we describe the use of N-Boc protected hydrazine together with α-amino acid derived isocyanides in the Ugi tetrazole react...

Amine precursors such as NH-Boc (5) and NH-formyl (6) protected glycines were grafted by esterification on the hy-droxylated arms of 1-(2-hydroxyethyl)-3-methylimidazolium hexafluorophosphates 4h or tetrafluoroborates 4t. The Boc cleav-age was then realized at room temperature by successively treating acetonitrile solutions of the carbamates 7h or 7t with methanol and acetyl chloride (2 equival...