T his peripheral blood smear is from a 72-year-old woman, taken several hours before she died of recurrent plasma cell myeloma and newly developed secondary plasma cell leukemia. Her white blood cell count increased from 39.53 10/mL to 233.2 3 10/mL in 28 hours. The peripheral blood smear shows marked leukocytosis with numerous smallto medium-sized bizarre-looking cells (95% of white blood cell...

Fish hematology is one of the most recent branches of physiology to assess the status of general health. Blood is the transport medium, a defense system, and an acid/base buffer system. Circulating blood is the common denominator of health and illness and alteration in its chemical or cellular illness and composition can indicate hematological and nonhematological diseases. Erythrocytes occupy ...

The existence of multiple small fat droplets on the erythrocytes at peripheral blood smear is a very important characteristic in patients with very severe hypertriglyceridemia.

BACKGROUND Blood smear microscopic images are routinely investigated by haematologists to diagnose most blood diseases. However, the task is quite tedious and time consuming. An automatic detection and classification of white blood cells within such images can accelerate the process tremendously. In this paper we propose a system to locate white blood cells within microscopic blood smear images...

Light microscopy of blood smears for diagnosis of malaria in the field has several limitations, notably delays in diagnosis. This study in Ahmedabad in Gujarat State, India, evaluated the diagnostic performance of a rapid diagnostic test for malaria (SD Bioline Malaria Ag P.f/Pan) versus blood smear examination as the gold standard. All fever cases presenting at 13 urban health centres were sub...

A rapid test for diagnosis of malaria based on acridine orange staining of centrifuged blood samples in a microhaematocrit tube (QBC) was compared with Leishman stained thin peripheral blood smear in 287 samples. Malaria was diagnosed in 44 patients by Leishman staining technique and in 65 patients by QBC method. The QBC method allowed detection of an additional 21 cases. Thus the prevalence ra...

BACKGROUND Quick diagnosis of smear-negative pulmonary tuberculosis (TB) and extra-pulmonary TB are urgently needed in clinical diagnosis. Our research aims to investigate the usefulness of the interferon-γ release assay (IGRA) for the diagnosis of smear-negative pulmonary and extra-pulmonary TB. METHODS We performed TB antibody and TB-IGRA tests on 389 pulmonary TB patients (including 120 sm...

A new method for fast and simple segmentation of peripheral blood smears using Teager energy operator (TEO) is presented. The two-pan algorithm efficiently segments leucocytes present in the smear into nucleus and cytoplasm. The local mean weighted high pass filtering property of Teager energy operator is used to identify and distinguish the nucleus of white blood cells. Cytoplasm present in th...

A 78-year-old woman hospitalized for investigation of ascites presented with weakness, loss of appetite, fever, and chills. A complete blood count showed anemia, leukocytosis, and thrombocytopenia (hemoglobin, 8.5 g/dL; leukocytes, 27.5 3 10/L; platelets, 50 3 10/L). Peripheral blood smear demonstrated the presence of neutrophilia with left shift (promyelocytes, 0.3 3 10/L; myelocytes, 1.9 3 10...

BACKGROUND The existing World Health Organization diagnostic algorithms for smear-negative TB perform poorly in HIV-infected individuals. New TB diagnostics such as urine TB lipoarabinomannan (LAM) could improve the accuracy and reduce delays in TB diagnosis in HIV-infected smear-negative presumptive TB. We sought to determine predictors for MTB culture-positivity among these patients. METHOD...