Introduction: Since some dyes and their metabolites have toxicity and carcinogenicity potential, and are dangerous to the health of different living creatures, discharge of untreated wastewaters containing large concentrations of dye compounds into water resources is one of the important environmental problems. Therefore, in this research, the efficiency of chemical coagulation process was inve...

background: untreated leachate is being discharged into the environment in many countries worldwide. leachate treatment methods have not been unified so far due to the variable composition of leachate. moreover, the lack of appropriate treatment and disposal of leachate causes environmental pollution. this study aimed to compare removal efficiency of chemical oxygen demand (cod) and total suspe...

Antiphospholipid syndrome (APS) is characterized by recurrent thrombosis or pregnancy morbidity associated with antiphospholipid antibodies (aPL). Impaired fibrinolysis is a contributing factor for the development of thrombosis, and the effect of aPL in the fibrinolytic system has been investigated. Impaired release of tPA and enhanced release of PAI-1 after endothelial activation is reported i...

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Coagulation factor IX is a vitamin K-dependent glycoprotein that circulates in blood as a precursor of a serine protease. Incubation of human factor IX with human alpha-thrombin resulted in a time and enzyme concentration-dependent cleavage of factor IX yielding a molecule composed of a heavy chain (mol wt 50,000) and a doublet light chain (mol wt 10,000). The proteolysis of factor IX by thromb...

There is an epidemiological association between periodontitis and cardiovascular disease (CVD). In periodontitis, low grade systemic inflammation and bacteremia occur regularly. Such events may contribute to platelet activation and subsequent pro-coagulant state. This study aimed to investigate platelet activation in periodontitis patients. The study is composed of two parts. In the first part,...

Waste generated from the processing of marine organisms for food represents an underutilized resource that has the potential to provide bioactive molecules with pharmaceutical applications. Some of these molecules have known anti-thrombotic and anti-coagulant activities and are being investigated as alternatives to common anti-thrombotic drugs, like heparin and warfarin that have serious side e...