نتایج جستجو برای: blood cancer

تعداد نتایج: 1553562  

Journal: Nanomedicine Journal 2017
Mahboubeh Ebrahimian, Maryam Hashemi

The application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. In recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. On the other hand, encapsulation of drugs into nanoparticles (NPs) can improve...

Background: Venous thromboembolism (VTE) is a significant complication in cancer patients which was found in 4-20% of the patients. This study was aimed to evaluate risk factors of deep vein thrombosis (DVT) in cancer patients in an oncology center in Indonesia.  Methods: This was a retrospective cohort study. Data were obtained from medical records of adult cancer patients with DVT referring ...

Background and purpose: CYP1B1 is involved in the metabolism of exogenous and endogenous substrates and plays a key role in hormone and xenobiotic induced carcinogenesis. Polymorphisms in CYP1B1 could result in modifications in its enzyme activity and are known to be associated with cancer susceptibility related to environmental toxins and hormone exposure. Moreover, the association of CYP1B1 p...

بیگلریان, اکبر, رهگذر, مهدی, شاهی, فرهاد, صفار, اعظم,

Background: Blood cancer (leukemia) is the cancer of blood tissue and Acute Myeloid Leukemia (AML) is the third most prevalent type in Iran. Survival time after diagnosis and its risk factors are one of the most important indicators for assessing the treatment. Methods: Data for this prospective study belong to Valiasr 2 (Imam Khomeini Hospital) AML patients during 2008-2013. A total of 85 p...

2012
Zhiwei Wang Lei Liu Jun Ji Jianian Zhang Min Yan Jun Zhang Bingya Liu Zhenggang Zhu Yingyan Yu

This study focuses on the association between the ABO blood group system and the risk of gastric cancer or Helicobacter pylori infection. The data for the ABO blood group was collected from 1045 cases of gastric cancer, whereby the patient underwent a gastrectomy in Ruijin Hospital, Shanghai. The information on the ABO blood group from 53,026 healthy blood donors was enrolled as control. We sea...

ژورنال: پژوهش در پزشکی 2009
خاتمی*1،, فاطمه, زالی1, محمد رضا, سلطانی1،, معصومه, غیاثی1،, سمیه, محبی1،, سید رضا, منتظر حقیقی1،, مهدی,

Abstract Background: Sporadic colorectal cancer is the fourth most common cancer in Iran. The DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) is involved in the cellular defense against alkylating agents. Genetic alterations in the MGMT gene may impair the protein’s ability to remove alkyl groups from the O6-position of guanine, thereby raising the mutation rate and increasi...

Journal: :International Journal of Epidemiology 2021

Abstract Background Metabolomics studies in cancer epidemiology have mostly focused on single metabolite-cancer site associations. Pan-cancer analyses may larger statistical power when identifying metabolites showing consistent associations across sites, while allowing the identification of site-specific Methods Data from seven cancer-specific case-control nested within European Prospective Inv...

Journal: :مجله دانشگاه علوم پزشکی کرمانشاه 0
sirous naeimi dept. of biology, islamic azad university, kazeroon kambiz bagheri dept. of biology, islamic azad university, kazeroon nasrollah erfani shiraz institute for cancer research, shiraz university of medical sciences, shiraz

background: ovarian cancer is a relatively common cancer among postmenopausal women. nowadays, there is controversy about immunotherapy of ovarian cancer patients with interleukins such as interferon to reach better out come in prognosis of patients under chemotherapy. ctla-4 is a gene, which has an important role in homeostasis and regulation of immune response. inhibitory nature of ctla-4 is ...

ژورنال: پژوهش در پزشکی 2017

Background and Aim: Lung cancer is the most common cause of cancer-related deaths wordwide and non-small cell lung cancer (NSCLC), especially adenocarcinoma, is the most common type of lung cancer. Most cases of adenocarcinoma will occur due to KRAS mutations or EGFR mutations and amplifications. The polymorphism rs884225 which is associated with increased EGFR expression is located in the 3'UT...

ژورنال: پژوهش در پزشکی 2004
Ann Dalton, , David p. Hornby, , وحید رضا یاسایی, ,

Background: Breast cancer is the most common female malignancy and the main cause of death in  mid-aged women. Genetic germ line mutations in BRCAI/BRCA2 in Iranian women with breast or  ovarian cancer have not been yet reported. Materials and methods: Clinical data, family history and blood samples were obtained from 83  females aged less than 45 years with primary breast cancer in order to su...

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