background: immune reactions have been reported to be involved in the destruction of retinal ganglion cells (rgcs) in glaucoma. objective: to investigate the role of major histocompatibility complex class i-related chain a and b (mica and micb) molecules in the pathogenesis of glaucoma. methods: aqueous humor and serum samples from 15 glaucoma patients and 45 patients with cataract, undergoing ...

Humor and laughter have been thought to be beneficial for thousands of years. Although much has been written on this subject, there is very little written about the actual use of humor in practice. This article reviews the role that humor and laughter may play in medicine in general and palliative care in particular. In addition, it introduces a model that clinicians can follow when trying to i...

The effects of vitreous humor and some of its components on the function of rabbit corneal endothelium were investigated and compared to those of artificial and natural aqueous humor. The rate of fluid pumping across the endothelium was measured while that layer was in contact with: (1) complete medium, an artificial aqueous solution; (2) pooled rabbit aqueous humor; (3) filtered and (4) unfilt...

This paper deals with a contribution of computational analysis of verbal humor to natural language cognition. After a brief introduction to the growing area of computational humor and of its roots in humor theories, it describes and compares the results of a human-subject and computer experiment. The specific interest is to compare how well the computer, equipped with the resources and methodol...

.he ability of the cardiac glycosides, ouabain and digoxin, to lower eye pressure-' '' '-• has been ascribed to a primary inhibition of aqueous humor inflow. In the cat, which is the experimental animal of this study, the effect of ouabain on aqueous humor inflow is not clear. The previous report, which indicated that aqueous humor formation of the cat was decreased by ouabain, was based upon r...

PURPOSE To determine whether glaucoma patients exhibit an abnormal melatonin concentration in aqueous humor. DESIGN Case-controlled study, laboratory investigation. METHODS Aqueous humor and plasma samples of 28 patients with primary open-angle glaucoma and 31 nonglaucoma control patients were collected during surgery, and additional plasma samples were taken the night preceding surgery. Me...

In this paper we explore Computer-Aided Humor (CAH), where a computer and a human collaborate to be humorous. CAH systems support people’s natural desire to be funny by helping them express their own idiosyncratic sense of humor. Artificial intelligence research has tried for years to create systems that are funny, but found the problem to be extremely hard. We show that by combining the streng...

Activated complement is an important mediator of inflammation. Radioimmunoassay was used to measure levels of C3a, an activated fragment of C3, in aqueous humor. Additionally, immunoelectrophoresis was performed on aqueous humor to detect Factor B and its conversion product, Bb, as well as C3c, a breakdown product of C3. All six samples of normal aqueous humor had no detectable C3a, C3c, or Fac...

PURPOSE To investigate the aqueous humor proteome in patients with glaucoma and a control group. METHOD Aqueous humor was obtained from five human donors diagnosed with primary open angle glaucoma (POAG) and five age- and sex-matched controls undergoing cataract surgery. Quantitative proteome analysis of the aqueous humor by hyper reaction monitoring mass spectrometry (HRM-MS) based on SWATH ...

M edicine is serious business, but physicians have always tried to balance the heavier aspects of their work with humor and lightness. Hippocrates, for example, wrote that physicians should cultivate a serious and respectable image, but at the same time he advised them to use wit in interacting with their patients because “dourness is repulsive both to the healthy and to the sick.” While humor ...