OBJECTIVE To identify and describe correlates of medication adherence in a large, national sample of outpatients with bipolar disorder. METHOD Data were collected via a self-report, Web-based survey in January and February of 2008 from US patients aged 18-65 years who reported a diagnosis of bipolar disorder and current use of psychotropic medication. Patients with a Composite International D...

BACKGROUND Despite cerebrovascular diseases having been reported as one of the major causes of death among patients with bipolar disorder, there is scant information on the risk of stroke among this patient population. This study estimated the relative risk of developing stroke among patients with bipolar disorder in 6 years following hospitalization for an acute mood episode compared with pati...

BACKGROUND The morbidity associated with bipolar disorder is, in part, responsible for repeated calls for improved detection and recognition. No such commentary exists for the improved detection of borderline personality disorder. Clinical experience suggests that it is as disabling as bipolar disorder, but no study has directly compared the two disorders. AIMS To compare the levels of psycho...

BACKGROUND Bipolar disorder is a severe psychiatric disorder with high heritability. Co-morbid conditions are common and might define latent subgroups of patients that are more homogeneous with respect to genetic risk factors. METHODOLOGY In the Caucasian GAIN bipolar disorder sample of 1000 cases and 1034 controls, we tested the association of single nucleotide polymorphisms with patient sub...

BACKGROUND Global mental health is a growing field intricately connected to broader health, violence and economic issues. Despite the high prevalence and cost of mental health disorders, an estimated 75 % of those with need in lower resource settings do not receive intervention. Most studies to date have examined the effectiveness of single-disorder mental health treatments - an approach that m...

Imparting bad news had always been an unpleasant task for the physician, as shown from ancient years to our days. In the healthcare sector and as far as the cancer patient is concerned, the imparting of bad news is performed by the patient's doctor within a therapeutic relationship of course. The fundamental question is how a therapist could tailor the information to any patient and if "Is it p...

Results Of CMHT patients, 44% (95% CI 38.1^49.9) reportedpast-year problem druguse and/orharmful alcoholuse; 75% (95% CI 68.2^80.2) of drug service and 85% of alcohol service patients (95% CI 74.2^93.1) had a past-year psychiatric disorder.Mostcomorbiditypatients appear ineligible forcross-referral between services.Large proportions are not identifiedby services andreceive no specialist interve...

OBJECTIVE To compare the outcome of children with anterior epistaxis treated intraoperatively with either bipolar electrocautery or silver nitrate chemical cautery. STUDY DESIGN Case series with chart review. SETTING Tertiary-care pediatric otolaryngology practice. SUBJECTS Children aged 2 to 18 years treated with either intraoperative bipolar electrocautery or silver nitrate chemical cau...

UNLABELLED Alcoholism is present in approximately 40-60% of bipolar patients. This comorbidity between bipolar disorder and alcoholism is high and may result from existence of common genetic factors for the two disorders. In both disorders, dysregulation of the dopaminergic neurotransmission had been implicated. Association analyses revealed several candidate genes acting in the dopaminergic pa...

Abstract Background Different treatment options are available for the management of BPH. Our study aimed to compare surgical outcomes a holmium laser enucleation prostate (HoLEP) and bipolar transurethral resection (Bipolar-TURP) after 2 years. Methods prospective randomized included 114 patients: 55 patients underwent HoLEP procedure 59 TURP procedure. All complete preoperative assessment phys...